Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 18/20 | 0.42 |
| ▸ | HTR1A | P08908 | 17/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | NOS3 | P29474 | 1/20 | 0.34 |
| ▸ | NOS1 | P29475 | 1/20 | 0.34 |
| ▸ | NOS2 | P35228 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6615278 | 0.91 | HTR1A (0.39) | SLC6A4HTR1AKCNH2NOS3NOS1 | |
| SCHEMBL6614311 | 0.89 | SLC6A4 (0.42) | SLC6A4HTR1A | |
| SCHEMBL6617295 | 0.87 | HTR1A (0.54) | SLC6A4HTR1A | |
| SCHEMBL6617238 | 0.85 | HTR1A (0.48) | SLC6A4HTR1ACYP2D6 | |
| SCHEMBL6418986 | 0.85 | HTR1A (0.43) | SLC6A4HTR1AKCNH2CYP2D6NOS3 | |
| SCHEMBL6416533 | 0.85 | HTR1A (0.43) | SLC6A4HTR1AKCNH2CYP2D6NOS3 | |
| SCHEMBL6613494 | 0.85 | HTR1A (0.49) | SLC6A4HTR1ACYP2D6 | |
| SCHEMBL6614527 | 0.82 | SLC6A4 (0.43) | SLC6A4HTR1ASLC6A2 | |
| SCHEMBL6618151 | 0.81 | CCR3 (0.38) | SLC6A4HTR1AKCNH2SLC6A2 | |
| SCHEMBL6615152 | 0.81 | ALDH1A1 (0.47) | SLC6A4HTR1ASLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1466901-A1 | SEROTONINE REUPTAKE INHIBITOR | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2004-10-13 | — | — | EP | disclosed |