Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 7/20 | 0.43 |
| ▸ | HTR1A | P08908 | 2/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.41 |
| ▸ | CCR3 | P51677 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 3/20 | 0.37 |
| ▸ | DRD3 | P35462 | 3/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | ATM | Q13315 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6613548 | 0.91 | SLC6A4 (0.41) | SLC6A4HTR1ASLC6A2DRD2ALDH1A1 | |
| SCHEMBL6614469 | 0.91 | SLC6A4 (0.42) | SLC6A4HTR1ASLC6A2ATM | |
| SCHEMBL6619955 | 0.89 | HTR1A (0.58) | SLC6A4HTR1A | |
| SCHEMBL6617933 | 0.88 | HTR1A (0.47) | SLC6A4HTR1ACCR3KCNH2ALDH1A1 | |
| SCHEMBL6617633 | 0.88 | HTR1A (0.47) | SLC6A4HTR1ACCR3DRD2DRD3 | |
| SCHEMBL6617668 | 0.86 | SLC6A4 (0.46) | SLC6A4HTR1ASLC6A2CCR3DRD2 | |
| SCHEMBL6420020 | 0.85 | SLC6A4 (0.44) | SLC6A4HTR1ASLC6A2CCR3DRD2 | |
| SCHEMBL6418595 | 0.85 | SLC6A4 (0.44) | SLC6A4HTR1ASLC6A2CCR3DRD2 | |
| SCHEMBL6614256 | 0.82 | CCR3 (0.39) | SLC6A4HTR1ASLC6A2CCR3DRD2 | |
| SCHEMBL6614326 | 0.81 | SLC6A4 (0.42) | SLC6A4HTR1ASLC6A2CCR3DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1466901-A1 | SEROTONINE REUPTAKE INHIBITOR | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2004-10-13 | — | — | EP | disclosed |