Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 15/20 | 0.58 |
| ▸ | SLC6A4 | P31645 | 14/20 | 0.58 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6617933 | 0.91 | HTR1A (0.47) | HTR1ASLC6A4 | |
| SCHEMBL6617633 | 0.91 | HTR1A (0.47) | HTR1ASLC6A4 | |
| SCHEMBL6615354 | 0.90 | HTR1A (0.58) | HTR1ASLC6A4 | |
| SCHEMBL6614532 | 0.89 | SLC6A4 (0.43) | HTR1ASLC6A4 | |
| SCHEMBL6613548 | 0.88 | SLC6A4 (0.41) | HTR1ASLC6A4MEN1KMT2A | |
| SCHEMBL6616119 | 0.87 | HTR1A (0.62) | HTR1ASLC6A4SIGMAR1MEN1POLB | |
| SCHEMBL6411217 | 0.86 | HTR1A (0.60) | HTR1ASLC6A4SIGMAR1MEN1POLB | |
| SCHEMBL6420167 | 0.86 | HTR1A (0.60) | HTR1ASLC6A4SIGMAR1MEN1POLB | |
| SCHEMBL6617264 | 0.83 | HTR1A (0.52) | HTR1ASLC6A4 | |
| SCHEMBL6612884 | 0.83 | HTR1A (0.56) | HTR1ASLC6A4SIGMAR1MEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1466901-A1 | SEROTONINE REUPTAKE INHIBITOR | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2004-10-13 | — | — | EP | disclosed |