Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 5/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | HRH1 | P35367 | 11/20 | 0.38 |
| ▸ | CCR3 | P51677 | 11/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 9/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6619955 | 0.91 | HTR1A (0.58) | HTR1ASLC6A4 | |
| SCHEMBL6614964 | 0.90 | HTR1A (0.48) | HTR1ASLC6A4CYP2D6 | |
| SCHEMBL6617933 | 0.90 | HTR1A (0.47) | HTR1ASLC6A4CYP2D6HRH1CCR3 | |
| SCHEMBL6417878 | 0.88 | HTR1A (0.48) | HTR1ASLC6A4CYP2D6HRH1CCR3 | |
| SCHEMBL6614532 | 0.88 | SLC6A4 (0.43) | HTR1ASLC6A4CCR3KCNH2DRD2 | |
| SCHEMBL6614951 | 0.87 | HTR1A (0.51) | HTR1ASLC6A4CYP2D6HRH1CCR3 | |
| SCHEMBL6415175 | 0.87 | HTR1A (0.48) | HTR1ASLC6A4CYP2D6HRH1CCR3 | |
| SCHEMBL6613548 | 0.86 | SLC6A4 (0.41) | HTR1ASLC6A4DRD2 | |
| SCHEMBL6615132 | 0.85 | HTR1A (0.45) | HTR1ASLC6A4CYP2D6HRH1CCR3 | |
| SCHEMBL6616160 | 0.84 | HTR1A (0.43) | HTR1ASLC6A4CYP2D6HRH1CCR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1466901-A1 | SEROTONINE REUPTAKE INHIBITOR | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2004-10-13 | — | — | EP | disclosed |