Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 6/20 | 0.51 |
| ▸ | HTR1A | P08908 | 5/20 | 0.51 |
| ▸ | MAOB | P27338 | 5/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 4/20 | 0.38 |
| ▸ | MAOA | P21397 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | CCR3 | P51677 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6616119 | 0.92 | HTR1A (0.62) | SLC6A4HTR1AACHEMEN1POLB | |
| SCHEMBL6616780 | 0.91 | HTR1A (0.50) | SLC6A4HTR1AMAOBCYP2D6 | |
| SCHEMBL6614951 | 0.90 | HTR1A (0.51) | SLC6A4HTR1AMAOBCYP2D6ALDH1A1 | |
| SCHEMBL6617668 | 0.88 | SLC6A4 (0.46) | SLC6A4HTR1AALDH1A1ATMACHE | |
| SCHEMBL6617933 | 0.87 | HTR1A (0.47) | SLC6A4HTR1AMAOBCYP2D6ALDH1A1 | |
| SCHEMBL6413456 | 0.86 | HTR1A (0.52) | SLC6A4HTR1AMAOBCYP2D6ALDH1A1 | |
| SCHEMBL6418328 | 0.86 | SLC6A4 (0.52) | SLC6A4HTR1AMAOBCYP2D6ALDH1A1 | |
| SCHEMBL6615215 | 0.86 | SLC6A4 (0.45) | SLC6A4HTR1AALDH1A1ATMMEN1 | |
| SCHEMBL6615657 | 0.84 | HTR1A (0.49) | SLC6A4HTR1AMAOBCYP2D6ALDH1A1 | |
| SCHEMBL6615659 | 0.83 | HTR1A (0.42) | SLC6A4HTR1AMAOBCYP2D6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1466901-A1 | SEROTONINE REUPTAKE INHIBITOR | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2004-10-13 | — | — | EP | disclosed |