Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 8/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 8/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 3/20 | 0.34 |
| ▸ | PTGDR | Q13258 | 2/20 | 0.34 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.34 |
| ▸ | HRH1 | P35367 | 3/20 | 0.34 |
| ▸ | CCR3 | P51677 | 3/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6418997 | 0.94 | HTR1A (0.43) | HTR1ASLC6A4CYP2D6P2RX7FFAR4 | |
| SCHEMBL6412814 | 0.91 | HTR1A (0.52) | HTR1ASLC6A4ACHEHTR4 | |
| SCHEMBL6416366 | 0.90 | HTR1A (0.42) | HTR1ASLC6A4CYP2D6P2RX7ACHE | |
| SCHEMBL6414341 | 0.90 | HTR1A (0.49) | HTR1ASLC6A4CYP2D6 | |
| SCHEMBL6616160 | 0.89 | HTR1A (0.43) | HTR1ASLC6A4CYP2D6FFAR4ACHE | |
| SCHEMBL6411727 | 0.87 | P2RX7 (0.44) | HTR1ASLC6A4P2RX7ACHEHTR4 | |
| SCHEMBL6410415 | 0.85 | PER2 (0.39) | HTR1ASLC6A4P2RX7ACHEHTR4 | |
| SCHEMBL6414775 | 0.84 | HTR1A (0.42) | HTR1ASLC6A4CYP2D6FFAR4ACHE | |
| SCHEMBL6415277 | 0.84 | HTR1A (0.52) | HTR1ASLC6A4P2RX7CCR3 | |
| SCHEMBL6412226 | 0.83 | HTR1A (0.49) | HTR1ASLC6A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1466901-A1 | SEROTONINE REUPTAKE INHIBITOR | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2004-10-13 | — | — | EP | disclosed |