Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.43 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.43 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.43 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.43 |
| ▸ | CTSA | P10619 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | USP2 | O75604 | 2/20 | 0.40 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2469969 | 0.91 | ALDH1A1 (0.46) | HSD17B10KDM4EALDH1A1ADORA3HSP90AA1 | |
| SCHEMBL15065891 | 0.88 | KDM4E (0.44) | HSD17B10KDM4EALDH1A1ADORA3MAPK1 | |
| SCHEMBL6613757 | 0.83 | ADORA3 (0.58) | KDM4EALDH1A1ADORA3MEN1KMT2A | |
| SCHEMBL2469712 | 0.81 | HSP90AA1 (0.54) | KDM4EALDH1A1HSP90AA1HSP90AB1MAPK1 | |
| SCHEMBL3859281 | 0.81 | HSD17B10 (0.38) | HSD17B10KDM4EALDH1A1ADORA3 | |
| SCHEMBL15063499 | 0.81 | S1PR4 (0.40) | HSD17B10KDM4EALDH1A1ADORA3MAPK1 | |
| SCHEMBL17797252 | 0.80 | PYGL (0.39) | HSD17B10KDM4EALDH1A1ADORA3KMT2A | |
| SCHEMBL1919622 | 0.80 | ALDH1A1 (0.38) | HSD17B10KDM4EALDH1A1ADORA3TSHR | |
| SCHEMBL3836713 | 0.79 | ALDH1A1 (0.38) | HSD17B10KDM4EALDH1A1ADORA3MEN1 | |
| SCHEMBL3842956 | 0.79 | ADORA3 (0.36) | HSD17B10KDM4EALDH1A1ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1414814-A1 | 6-ARYL-4-AMINOPICOLINATES AND THEIR USE AS HERBICIDES | Dow Agrosciences LLC (US) | 2004-05-06 | — | — | EP | disclosed |
| WO-2003011853-A1 | 6-ARYL-4-AMINOPICOLINATES AND THEIR USE AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 2003-02-13 | — | — | WO | disclosed |