Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 8/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 6/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | THPO | P40225 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6615968 | 0.79 | PTGS2 (0.57) | PTGS2PTGS1CYP1A2CYP2C9HTT | |
| SCHEMBL3753336 | 0.78 | MKNK1 (0.36) | PTGS2PTGS1HTTMAPT | |
| SCHEMBL10415458 | 0.78 | SMN1; SMN2 (0.44) | PTGS1TSHRNPSR1SMN1; SMN2HPGD | |
| SCHEMBL31406162 | 0.77 | PTGS2 (0.39) | PTGS2PTGS1SMN1; SMN2HPGDL3MBTL1 | |
| SCHEMBL16202001 | 0.76 | CYP1A2 (0.48) | PTGS2PTGS1CYP1A2CYP2C9HTT | |
| SCHEMBL6615348 | 0.76 | CYP1A2 (0.48) | PTGS2PTGS1CYP1A2CYP2C9HTT | |
| SCHEMBL6132524 | 0.75 | CYP1A2 (0.47) | PTGS2CYP1A2CYP2C9HTTADORA3 | |
| SCHEMBL22897465 | 0.75 | CYP1A2 (0.47) | PTGS2PTGS1CYP1A2CYP2C9HTT | |
| SCHEMBL22173634 | 0.74 | CHRNA7 (0.46) | PTGS2PTGS1ADORA3MAPT | |
| SCHEMBL6616454 | 0.73 | P2RX7 (0.43) | PTGS2PTGS1CYP1A2CYP2C9HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1442026-A1 | TRIAZOLE DERIVATIVES AS CYCLOOXYGENASE (COX) INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-08-04 | — | — | EP | claimed |
| WO-2003040110-A1 | TRIAZOLE DERIVATIVES AS CYCLOOXYGENASE (COX) INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-05-15 | — | — | WO | claimed |
| CN-119569663-A | Preparation method of 1- (3-bromo-4-methoxyphenyl) -3- (trifluoromethyl) -1,2, 4-triazole | 无锡捷化医药科技有限公司 | 2025-03-07 | — | — | CN | disclosed |
| WO-2004060367-A1 | IMIDAZOLE AND TRIAZOLE DERIVATIVES USEFUL AS SELECTIVE COX-1 INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-07-22 | — | — | WO | disclosed |