Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 18/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 18/20 | 0.52 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.37 |
| ▸ | CCR3 | P51677 | 1/20 | 0.37 |
| ▸ | CCR5 | P51681 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6615659 | 0.91 | HTR1A (0.42) | HTR1ASLC6A4 | |
| SCHEMBL6616160 | 0.91 | HTR1A (0.43) | HTR1ASLC6A4CCR3 | |
| SCHEMBL6612883 | 0.89 | SLC6A4 (0.53) | HTR1ASLC6A4 | |
| SCHEMBL6614256 | 0.89 | CCR3 (0.39) | HTR1ASLC6A4OPRM1OPRK1OPRL1 | |
| SCHEMBL6615686 | 0.87 | SLC6A4 (0.37) | HTR1ASLC6A4OPRM1OPRK1OPRL1 | |
| SCHEMBL6415277 | 0.86 | HTR1A (0.52) | HTR1ASLC6A4OPRM1OPRK1OPRL1 | |
| SCHEMBL6412814 | 0.86 | HTR1A (0.52) | HTR1ASLC6A4OPRM1OPRK1OPRL1 | |
| SCHEMBL6615651 | 0.84 | HTR1A (0.49) | HTR1ASLC6A4OPRM1OPRK1CCR3 | |
| SCHEMBL6619955 | 0.83 | HTR1A (0.58) | HTR1ASLC6A4 | |
| SCHEMBL6616119 | 0.82 | HTR1A (0.62) | HTR1ASLC6A4CCR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1466901-A1 | SEROTONINE REUPTAKE INHIBITOR | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2004-10-13 | — | — | EP | disclosed |