Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.36 |
| ▸ | PER2 | O15055 | 3/20 | 0.35 |
| ▸ | CCR3 | P51677 | 2/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | CCR5 | P51681 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.34 |
| ▸ | FPR2 | P25090 | 1/20 | 0.34 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6614256 | 0.91 | CCR3 (0.39) | SLC6A4HTR2AHTR2CHTR1AOPRM1 | |
| SCHEMBL6614883 | 0.89 | SLC6A4 (0.43) | SLC6A4HTR1AOPRM1OPRK1OPRL1 | |
| SCHEMBL6617264 | 0.87 | HTR1A (0.52) | SLC6A4HTR1AOPRM1OPRK1OPRL1 | |
| SCHEMBL6410415 | 0.86 | PER2 (0.39) | SLC6A4HTR2AHTR2CHTR1AOPRM1 | |
| SCHEMBL6411836 | 0.86 | P2RX7 (0.39) | SLC6A4HTR2AHTR2CHTR1AOPRM1 | |
| SCHEMBL6616160 | 0.86 | HTR1A (0.43) | SLC6A4HTR1ACCR3ALDH1A1MCOLN3 | |
| SCHEMBL6615659 | 0.86 | HTR1A (0.42) | SLC6A4HTR1AALDH1A1ACHEHTR4 | |
| SCHEMBL6613548 | 0.83 | SLC6A4 (0.41) | SLC6A4HTR1AALDH1A1DRD2DRD4 | |
| SCHEMBL6613566 | 0.82 | OPRM1 (0.36) | SLC6A4HTR2AHTR2CHTR1AOPRM1 | |
| SCHEMBL6615215 | 0.82 | SLC6A4 (0.45) | SLC6A4HTR1ACCR3ALDH1A1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1466901-A1 | SEROTONINE REUPTAKE INHIBITOR | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2004-10-13 | — | — | EP | disclosed |