Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 3/20 | 0.40 |
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.40 |
| ▸ | HIPK4 | Q8NE63 | 3/20 | 0.40 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.40 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.40 |
| ▸ | CDK1 | P06493 | 2/20 | 0.40 |
| ▸ | CSF1R | P07333 | 2/20 | 0.40 |
| ▸ | CDK2 | P24941 | 2/20 | 0.40 |
| ▸ | FLT4 | P35916 | 2/20 | 0.40 |
| ▸ | CLK2 | P49760 | 2/20 | 0.40 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.40 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.40 |
| ▸ | STK3 | Q13188 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6612158 | 0.79 | MAOA (0.62) | SMN1; SMN2KDM4ENPC1ALDH1A1RAB9A | |
| SCHEMBL6613245 | 0.79 | MAOA (0.48) | SMN1; SMN2KDM4ENPC1ALDH1A1RAB9A | |
| SCHEMBL6613286 | 0.78 | MAOA (0.36) | SMN1; SMN2KDM4ENPC1ALDH1A1RAB9A | |
| SCHEMBL6614642 | 0.76 | SMN1; SMN2 (0.40) | SMN1; SMN2KDM4ENPC1ALDH1A1RAB9A | |
| SCHEMBL2242151 | 0.74 | SMN1; SMN2 (0.71) | SMN1; SMN2KDM4ENPC1ALDH1A1RAB9A | |
| SCHEMBL3038281 | 0.69 | ITGB1 (0.42) | SMN1; SMN2MAOAADRA1AMAPTTP53 | |
| SCHEMBL19029185 | 0.68 | HDAC6 (0.68) | — | |
| SCHEMBL6614014 | 0.67 | KDM4E (0.58) | SMN1; SMN2KDM4ENPC1ALDH1A1MAPK1 | |
| SCHEMBL19664253 | 0.66 | NPC1 (0.68) | SMN1; SMN2KDM4ENPC1ALDH1A1RAB9A | |
| SCHEMBL6614228 | 0.66 | HPSE (0.55) | KDM4EITGB1ITGA4ITGB7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040209776-A1 | Azole derivatives useful as insecticide | FAROOQ SALEEM | 2004-10-21 | — | — | US | disclosed |
| EP-1414818-A1 | AZOLE DERIVATIVES USEFUL AS INSECTICIDE | Syngenta Limited (GB) | 2004-05-06 | — | — | EP | disclosed |
| WO-2003011861-A1 | AZOLE DERIVATIVES USEFUL AS INSECTICIDE | SYNGENTA LIMITED (GB) | 2003-02-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040209776-A1 | Azole derivatives useful as insecticide | CYP8B1, HRH2, API5 | SMN1; SMN2 3030/4885KDM4E 1730/4885NPC1 4404/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.