Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | PDE9A | O76083 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6615278 | 0.90 | HTR1A (0.39) | SLC6A4OPRM1OPRL1OPRK1OPRD1 | |
| SCHEMBL6613566 | 0.90 | OPRM1 (0.36) | CCR3SLC6A4OPRM1OPRL1OPRK1 | |
| SCHEMBL6615651 | 0.88 | HTR1A (0.49) | CCR3SLC6A4OPRM1OPRK1OPRD1 | |
| SCHEMBL6618742 | 0.86 | HTR1A (0.40) | SLC6A4HTR1A | |
| SCHEMBL6613564 | 0.86 | HTR1A (0.41) | CCR3SLC6A4OPRM1OPRL1HTR1A | |
| SCHEMBL6410308 | 0.84 | CCR3 (0.39) | CCR3SLC6A4OPRM1OPRL1OPRK1 | |
| SCHEMBL6415111 | 0.84 | CCR3 (0.41) | CCR3SLC6A4OPRM1OPRL1OPRK1 | |
| SCHEMBL6614256 | 0.82 | CCR3 (0.39) | CCR3SLC6A4OPRM1OPRL1OPRK1 | |
| SCHEMBL6618608 | 0.81 | SLC6A4 (0.42) | SLC6A4SLC6A2HTR1AKCNH2 | |
| SCHEMBL6614326 | 0.80 | SLC6A4 (0.42) | CCR3SLC6A4SLC6A2HTR1ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1466901-A1 | SEROTONINE REUPTAKE INHIBITOR | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2004-10-13 | — | — | EP | disclosed |