Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 9/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4463271 | 0.80 | LMNA (0.68) | SLC6A4SLC6A2SLC6A3LMNASIGMAR1 | |
| SCHEMBL11251072 | 0.77 | SLC6A4 (0.55) | SLC6A4SLC6A2SLC6A3LMNASIGMAR1 | |
| SCHEMBL6421876 | 0.77 | LMNA (0.64) | SLC6A4SLC6A2SLC6A3LMNARAB9A | |
| SCHEMBL21809307 | 0.74 | KDM4E (0.41) | SLC6A4SLC6A2SLC6A3OPRD1ALDH1A1 | |
| SCHEMBL4039568 | 0.74 | SLC6A4 (0.51) | SLC6A4SLC6A2SLC6A3LMNARAB9A | |
| SCHEMBL9309772 | 0.73 | SLC6A4 (0.50) | SLC6A4SLC6A2SLC6A3LMNAOPRD1 | |
| SCHEMBL4560932 | 0.72 | SLC6A4 (0.51) | SLC6A4SLC6A2SLC6A3SIGMAR1OPRD1 | |
| SCHEMBL2905656 | 0.71 | LMNA (0.56) | SLC6A4SLC6A2SLC6A3LMNARAB9A | |
| SCHEMBL8234489 | 0.70 | LMNA (0.51) | SLC6A4SLC6A2SLC6A3LMNAOPRD1 | |
| SCHEMBL4131831 | 0.69 | SLC6A4 (0.63) | SLC6A4SLC6A2SLC6A3SIGMAR1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0891332-B1 | 6-PHENYLPYRIDYL-2-AMINE DERIVATIVES | PFIZER (US) | 2004-03-17 | — | — | EP | disclosed |