Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 7/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | P2RX7 | Q99572 | 7/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7004707 | 0.95 | ALOX5 (0.53) | ALOX5ALDH1A1L3MBTL1P2RX7TDP1 | |
| Fumaric Acid SCHEMBL7000167 | 0.93 | ALDH1A1 (0.52) | ALOX5ALDH1A1L3MBTL1DRD2DRD3 | |
| Fumaric Acid SCHEMBL7000170 | 0.93 | ALDH1A1 (0.52) | ALOX5ALDH1A1L3MBTL1DRD2DRD3 | |
| SCHEMBL8146601 | 0.91 | ALDH1A1 (0.55) | ALOX5ALDH1A1L3MBTL1DRD2DRD3 | |
| Hydrochloric Acid SCHEMBL6620924 | 0.90 | ALDH1A1 (0.54) | ALOX5ALDH1A1L3MBTL1DRD2DRD3 | |
| SCHEMBL6621938 | 0.82 | PARP14 (0.64) | DRD2DRD3 | |
| SCHEMBL6621536 | 0.82 | P2RX7 (0.45) | ALOX5P2RX7DRD2DRD3 | |
| Hydrochloric Acid SCHEMBL6617542 | 0.81 | ALOX5 (0.55) | ALOX5ALDH1A1L3MBTL1P2RX7 | |
| SCHEMBL8157925 | 0.81 | KMT2A (0.60) | ALDH1A1L3MBTL1 | |
| SCHEMBL6616803 | 0.81 | PARP14 (0.65) | DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0979231-B1 | CONDENSED PYRIDAZINE DERIVATIVES, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2004-11-24 | — | — | EP | disclosed |
| US-6248740-B1 | FOR SUPPRESSION OF HISTAMINE OR EOSINOPHIL CHEMOTAXIS TO TREAT ASTHMA; ANTIALLERGENIC | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-06-19 | — | — | US | disclosed |
| EP-0979231-A1 | CONDENSED PYRIDAZINE DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 2000-02-16 | — | — | EP | disclosed |
| WO-1998049167-A1 | CONDENSED PYRIDAZINE DERIVATIVES, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-11-05 | — | — | WO | disclosed |