Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR4 | P31391 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1952437 | 0.81 | ALDH1A1 (0.51) | — | |
| SCHEMBL6623293 | 0.74 | CXCR2 (0.48) | — | |
| SCHEMBL6618622 | 0.74 | ALDH1A1 (0.57) | SSTR4TSHR | |
| SCHEMBL7092842 | 0.73 | RAB9A (0.50) | TSHR | |
| SCHEMBL26750381 | 0.72 | ALDH1A1 (0.58) | SSTR4TSHR | |
| SCHEMBL6738543 | 0.72 | SSTR4 (0.39) | SSTR4 | |
| SCHEMBL11749561 | 0.72 | AR (0.50) | TSHR | |
| SCHEMBL11761868 | 0.72 | AR (0.47) | TSHR | |
| SCHEMBL6742061 | 0.71 | ALDH1A1 (0.47) | SSTR4CHEK1 | |
| SCHEMBL6736885 | 0.71 | ALDH1A1 (0.47) | SSTR4CHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1047695-B1 | NOVEL BISPIDINE ANTIARRHYTHMIC COMPOUNDS | ASTRAZENECA AB (SE) | 2004-03-17 | — | — | EP | disclosed |
| US-6291475-B1 | 3,7-DIAZABICYCLO(3.3.1)NONANE DERIVATIVES | ASTRAZENECA AB (SE) | 2001-09-18 | — | — | US | disclosed |