Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | HTR1D | P28221 | 1/20 | 0.46 |
| ▸ | HTR1B | P28222 | 1/20 | 0.46 |
| ▸ | HTR1F | P30939 | 1/20 | 0.46 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.39 |
| ▸ | SCD | O00767 | 2/20 | 0.38 |
| ▸ | DRD4 | P21917 | 3/20 | 0.38 |
| ▸ | RORC | P51449 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | SLC6A12 | P48065 | 1/20 | 0.37 |
| ▸ | SLC6A13 | Q9NSD5 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4081920 | 0.86 | SCD (0.40) | HTR1AHTR1DHTR1BHTR1FSCD | |
| SCHEMBL4076932 | 0.82 | HTR1A (0.39) | HTR1AHTR1DHTR1BHTR1FACSS2 | |
| SCHEMBL5871737 | 0.81 | SCD (0.45) | HTR1AHTR1DHTR1BHTR1FSCD | |
| SCHEMBL5871549 | 0.80 | HTT (0.39) | HTR1AHTR1DHTR1BHTR1FDRD2 | |
| SCHEMBL4073398 | 0.80 | ALDH1A1 (0.39) | HTR1AHTR1DHTR1BHTR1FDRD2 | |
| SCHEMBL5871706 | 0.80 | TACR1 (0.41) | HTR1AHTR1DHTR1BHTR1FSCD | |
| SCHEMBL5201280 | 0.80 | TACR1 (0.41) | HTR1AHTR1DHTR1BHTR1FSCD | |
| SCHEMBL544609 | 0.80 | SMN1; SMN2 (0.48) | HTR1AHTR1DHTR1BHTR1F | |
| SCHEMBL5871626 | 0.79 | HTT (0.39) | HTR1AHTR1DHTR1BHTR1F | |
| SCHEMBL5871563 | 0.79 | HTT (0.39) | HTR1AHTR1DHTR1BHTR1FACSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0976732-B1 | 1,4-SUBSTITUTED CYCLIC AMINE DERIVATIVES | EISAI CO LTD (JP) | 2004-11-24 | — | — | EP | claimed |