SCHEMBL662161

SCHEMBL662161

N#Cc1cc(Br)ccc1C(F)(F)F

nearest known ligand 0.43

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
AR P10275 15/20 0.43
SLC22A12 Q96S37 1/20 0.43
KIF11 P52732 1/20 0.40
PGR P06401 1/20 0.39
KDM1A O60341 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30945197 1.00 AR (0.43) ARSLC22A12KIF11PGRKDM1A
SCHEMBL1780774 0.88 MAOB (0.38) ARSLC22A12
SCHEMBL18212168 0.85 KIF11 (0.54) ARSLC22A12KIF11PGR
SCHEMBL21994516 0.85 MAOB (0.36) ARSLC22A12
SCHEMBL1226983 0.84 AR (0.56) ARPGR
SCHEMBL12070108 0.81 AR (0.56) AR
SCHEMBL15716096 0.80 MAOB (0.38) AR
SCHEMBL1996176 0.78 AR (0.53) ARSLC22A12KIF11
SCHEMBL325632 0.78 AR (0.50) ARSLC22A12KIF11PGR
SCHEMBL5203682 0.78 KIF11 (0.53) ARSLC22A12KIF11PGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12351565-B2 Aromatic compound and preparation method therefor and use thereof SHANGHAI ZHIGEN PHARMACEUTICAL & TECHNOLOGY CO., LTD. (CN) 2025-07-08 US disclosed
CN-111936476-B Aromatic compound and preparation method and application thereof 上海致根医药科技有限公司 2024-04-02 CN disclosed
US-11919882-B2 Organic molecules for use in organic optoelectronic devices SAMSUNG DISPLAY CO., LTD. (KR) 2024-03-05 US disclosed
EP-4316503-A1 PHARMACEUTICAL USE OF CYCLIC PEPTIDE COMPOUND CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2024-02-07 EP disclosed
EP-4043478-A1 CYCLIC PEPTIDE COMPOUND HAVING KRAS INHIBITING ACTION CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2022-08-17 EP disclosed
EP-3494112-B1 ORGANIC MOLECULES FOR USE IN ORGANIC OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2022-04-20 EP disclosed
US-11276825-B2 Organic molecules for use in organic devices CYNORA GMBH (DE) 2022-03-15 US disclosed
CN-109689643-B Organic molecules for organic optoelectronic devices 辛诺拉有限公司 2022-03-01 CN disclosed
US-20210184134-A1 ORGANIC MOLECULES FOR USE IN ORGANIC DEVICES SAMSUNG DISPLAY CO., LTD. (KR) 2021-06-17 US disclosed
US-20210171501-A1 ORGANIC MOLECULES FOR USE IN ORGANIC OPTOELECTRONIC DEVICES SAMSUNG DISPLAY CO., LTD. (KR) 2021-06-10 US disclosed
EP-2760868-A1 FURO[3,4-C]QUINOLINE DERIVATIVES, MEDICAMENTS CONTAINING SUCH COMPOUNDS, THEIR USE AND PROCESS FOR THEIR PREPARATION Boehringer Ingelheim International GmbH (DE) 2014-08-06 EP disclosed
EP-2675811-A1 TRICYCLIC PYRIDINE DERIVATIVES, MEDICAMENTS CONTAINING SUCH COMPOUNDS, THEIR USE AND PROCESS FOR THEIR PREPARATION Boehringer Ingelheim International GmbH (DE) 2013-12-25 EP disclosed
US-20130210850-A1 Furo[3,4-c]quinoline derivatives, medicaments containing such compounds, their use and process for their preparation BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2013-08-15 US disclosed
US-20130053404-A1 Tricyclic pyridine derivatives, medicaments containing such compounds, their use and process for their preparation BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2013-02-28 US disclosed
WO-2013024130-A1 FURO[3,4-C]QUINOLINE DERIVATIVES, MEDICAMENTS CONTAINING SUCH COMPOUNDS, THEIR USE AND PROCESS FOR THEIR PREPARATION BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2013-02-21 WO disclosed
CN-102869667-A Tricyclic pyridine derivatives, medicaments containing these compounds, their use and processes for their preparation BOEHRINGER INGELHEIM INT 2013-01-09 CN disclosed
EP-2536733-A1 TRICYCLIC PYRIDINE DERIVATIVES, MEDICAMENTS CONTAINING SUCH COMPOUNDS, THEIR USE AND PROCESS FOR THEIR PREPARATION Boehringer Ingelheim International GmbH (DE) 2012-12-26 EP disclosed
WO-2012110599-A1 TRICYCLIC PYRIDINE DERIVATIVES, MEDICAMENTS CONTAINING SUCH COMPOUNDS, THEIR USE AND PROCESS FOR THEIR PREPARATION BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2012-08-23 WO disclosed
US-20120046304-A1 TRICYCLIC PYRIDINE DERIVATIVES, MEDICAMENTS CONTAINING SUCH COMPOUNDS, THEIR USE AND PROCESS FOR THEIR PREPARATION BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2012-02-23 US disclosed
WO-2011101424-A1 TRICYCLIC PYRIDINE DERIVATIVES, MEDICAMENTS CONTAINING SUCH COMPOUNDS, THEIR USE AND PROCESS FOR THEIR PREPARATION BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2011-08-25 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210171501-A1 ORGANIC MOLECULES FOR USE IN ORGANIC OPTOELECTRONIC DEVICES L1CAM, OR10J3, AOX1 AR 3717/4885SLC22A12 2063/4885KIF11 3032/4885
US-20130210850-A1 Furo[3,4-c]quinoline derivatives, medicaments containing such compounds, their use and process for their preparation CETP, MTTP, NPC1L1 AR 4710/4885SLC22A12 1910/4885KIF11 3766/4885
US-12351565-B2 Aromatic compound and preparation method therefor and use thereof CYP4F11, PAH, COMT AR 1775/4885SLC22A12 692/4885KIF11 247/4885
US-20210184134-A1 ORGANIC MOLECULES FOR USE IN ORGANIC DEVICES CHRM1, C1S, DNMT3L AR 1523/4885SLC22A12 3463/4885KIF11 4512/4885
US-11276825-B2 Organic molecules for use in organic devices AOX1, OR10J3, L1CAM AR 720/4885SLC22A12 2069/4885KIF11 3612/4885
US-20130053404-A1 Tricyclic pyridine derivatives, medicaments containing such compounds, their use and process for their preparation CETP, MTTP, CES1 AR 4263/4885SLC22A12 3381/4885KIF11 4497/4885
US-20120046304-A1 TRICYCLIC PYRIDINE DERIVATIVES, MEDICAMENTS CONTAINING SUCH COMPOUNDS, THEIR USE AND PROCESS FOR THEIR PREPARATION CETP, MTTP, CES1 AR 4263/4885SLC22A12 3381/4885KIF11 4497/4885
US-11919882-B2 Organic molecules for use in organic optoelectronic devices L1CAM, OR10J3, AOX1 AR 3717/4885SLC22A12 2063/4885KIF11 3032/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.