SCHEMBL662183

SCHEMBL662183

CC(C(P)(c1ccccc1)c1ccccc1)(C(P)(c1ccccc1)c1ccccc1)C(P)(c1ccccc1)c1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.46
ALDH1A1 P00352 3/20 0.42
TAAR1 Q96RJ0 1/20 0.42
ALOX15 P16050 1/20 0.42
ESR1 P03372 2/20 0.41
ESR2 Q92731 2/20 0.41
CYP3A4 P08684 1/20 0.41
KCNN4 O15554 4/20 0.40
MAPT P10636 1/20 0.39
KMT2A Q03164 1/20 0.39
TSHR P16473 2/20 0.39
CYP2C19 P33261 1/20 0.38
HIF1A Q16665 1/20 0.38
CYP2B6 P20813 1/20 0.37
HDAC3 O15379 1/20 0.37
HDAC4 P56524 1/20 0.37
HDAC1 Q13547 1/20 0.37
HDAC7 Q8WUI4 1/20 0.37
HDAC2 Q92769 1/20 0.37
HDAC10 Q969S8 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16859261 0.97 MAPK1 (0.44) MAPK1ALDH1A1TAAR1ALOX15ESR1
SCHEMBL4988385 0.93 MAPK1 (0.41) MAPK1ALDH1A1TAAR1ALOX15ESR1
Formaldehyde SCHEMBL17495191 0.91 MAPK1 (0.39) MAPK1ALDH1A1TAAR1ALOX15ESR1
SCHEMBL3264960 0.83 MAPK1 (0.46) MAPK1ALDH1A1TAAR1ALOX15ESR1
SCHEMBL22032944 0.79 MAPK1 (0.42) MAPK1ALDH1A1TAAR1ALOX15ESR1
Bromide SCHEMBL8857061 0.79 MAPK1 (0.42) MAPK1ALDH1A1TAAR1ALOX15ESR1
SCHEMBL662176 0.79 MAPK1 (0.42) MAPK1ALDH1A1TAAR1ALOX15ESR1
SCHEMBL9190770 0.77 KCNN4 (0.43) MAPK1ALDH1A1TAAR1ALOX15ESR1
SCHEMBL842144 0.77 MAPK1 (0.50) MAPK1ALDH1A1TAAR1ALOX15ESR1
SCHEMBL3708602 0.77 MAPK1 (0.50) MAPK1ALDH1A1TAAR1ALOX15ESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 361 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12624276-B2 Compositions and methods for the dissolution of iron sulfide SOLUGEN, INC. (US) 2026-05-12 US claimed
EP-4590418-A1 WATER REMOVAL IN A PROCESS FOR PREPARING METHYLAL FROM CARBON DIOXIDE BASF SE (DE) 2025-07-30 EP claimed
EP-3694864-B1 BORONIC ACID DERIVATIVES AND SYNTHESIS THEREOF QPEX BIOPHARMA INC (US) 2025-03-05 EP claimed
US-20240368452-A1 COMPOSITIONS AND METHODS FOR THE DISSOLUTION OF IRON SULFIDE SOLUGEN, INC. (US) 2024-11-07 US claimed
WO-2024062017-A1 WATER REMOVAL IN A PROCESS FOR PREPARING METHYLAL FROM CARBON DIOXIDE BASF SE (DE) 2024-03-28 WO claimed
WO-2024062015-A1 PROCESS FOR REMOVING WATER FROM A MIXTURE CONTAINING METHANOL, WATER AND A CATALYST SYSTEM BASF SE (DE) 2024-03-28 WO claimed
US-11912731-B2 Use of silylated formiates as hydrosilane equivalents COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) 2024-02-27 US claimed
WO-2023156764-A1 PROCESS JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) 2023-08-24 WO claimed
EP-3962891-B1 METHOD FOR CATALYTICALLY PRODUCING UREA THYSSENKRUPP IND SOLUTIONS AG (DE) 2023-03-29 EP claimed
EP-3596038-B1 METAL-CATALYZED ALKOXYCARBONYLATION OF A LACTONE QATAR FOUND EDUCATION SCIENCE & COMMUNITY DEV (US) 2022-12-28 EP claimed
US-7615671-B2 Contacting a 1,2-dioxygenated organic compound under hydrogenation conditions in presence of catalyst composition comprising a ruthenium compound, trivalent phosphorus compound selected from 1,1,1-tris(diarylphosphinomethyl)alkyl or substituted alkyl, promoter selected from Lewis acids, protic acids EASTMAN CHEMICAL COMPANY (US) 2009-11-10 US claimed
US-20090143612-A1 HYDROGENATION PROCESS FOR THE PREPARATION OF 1,2-DIOLS EASTMAN CHEMICAL COMPANY (US) 2009-06-04 US claimed
US-20090043102-A1 METHOD FOR PRODUCING HETEROAROMATIC ALCOHOLS BASF SE (DE) 2009-02-12 US claimed
US-20090043046-A1 Process for producing functionalized polymers BRIDGESTONE CORPORATION (JP) 2009-02-12 US claimed
EP-2022803-A2 Process for producing functionalized polymers Bridgestone Corporation (JP) 2009-02-11 EP claimed
EP-0788405-A1 CATALYST FOR THE PREPARATION OF LINEAR CARBON MONOXIDE/ALPHA-OLEFIN COPOLYMERS THE DOW CHEMICAL COMPANY (US) 1997-08-13 EP claimed
US-5530162-A Process for the hydrogenation of aryl phosphines and products obtained therefrom RESEARCH CORPORATION TECHNOLOGIES, INC. (US) 1996-06-25 US claimed
WO-1996001690-A1 CATALYST FOR THE PREPARATION OF LINEAR CARBON MONOXIDE/ALPHA-OLEFIN COPOLYMERS THE DOW CHEMICAL COMPANY (US) 1996-01-25 WO claimed
WO-1993021192-A1 PROCESS FOR THE HYDROGENATION OF ARYL PHOSPHINES AND PRODUCTS OBTTAINED THEREFROM RESEARCH CORPORATION TECHNOLOGIES, INC. (US) 1993-10-28 WO claimed
US-4451680-A RUTHENIUM COMPOUND, BIDENTATE OR MULTIDENTATE PHOSPHINE, PHOSPHONIUM COMPOUND TEXACO INC. (US) 1984-05-29 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11912731-B2 Use of silylated formiates as hydrosilane equivalents PFAS, EPM2A, CYP2F1 MAPK1 2709/4885ALDH1A1 112/4885TAAR1 3490/4885
US-12624276-B2 Compositions and methods for the dissolution of iron sulfide MGAT2, SLC7A11, CA1 MAPK1 2141/4885ALDH1A1 990/4885TAAR1 1082/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.