Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 2/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | KCNN4 | O15554 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL662176 | 0.84 | MAPK1 (0.42) | MAPK1ALDH1A1TAAR1ALOX15ESR1 | |
| SCHEMBL662183 | 0.83 | MAPK1 (0.46) | MAPK1ALDH1A1TAAR1ALOX15ESR1 | |
| SCHEMBL16859261 | 0.81 | MAPK1 (0.44) | MAPK1ALDH1A1TAAR1ALOX15ESR1 | |
| SCHEMBL22032944 | 0.79 | MAPK1 (0.42) | MAPK1ALDH1A1TAAR1ALOX15ESR1 | |
| Bromide SCHEMBL8857061 | 0.79 | MAPK1 (0.42) | MAPK1ALDH1A1TAAR1ALOX15ESR1 | |
| SCHEMBL2012032 | 0.78 | MAPK1 (0.46) | MAPK1ALDH1A1TAAR1ALOX15ESR1 | |
| SCHEMBL4988385 | 0.77 | MAPK1 (0.41) | MAPK1ALDH1A1TAAR1ALOX15ESR1 | |
| SCHEMBL842144 | 0.77 | MAPK1 (0.50) | MAPK1ALDH1A1TAAR1ALOX15ESR1 | |
| SCHEMBL3708602 | 0.77 | MAPK1 (0.50) | MAPK1ALDH1A1TAAR1ALOX15ESR1 | |
| SCHEMBL9190770 | 0.77 | KCNN4 (0.43) | MAPK1ALDH1A1TAAR1ALOX15ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8455690-B2 | Method for producing arylhydroxylamine | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 2013-06-04 | — | — | US | disclosed |
| US-20100113830-A1 | METHOD FOR PRODUCING ARYLHYDROXYLAMINE | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 2010-05-06 | — | — | US | disclosed |
| EP-2154125-A1 | METHOD FOR PRODUCING ARYLHYDROXYLAMINE | Wako Pure Chemical Industries, Ltd. (JP) | 2010-02-17 | — | — | EP | disclosed |
| US-7618914-B2 | Method for producing hydroxylamine compound using platinum catalyst fixed on ion-exchange resin | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 2009-11-17 | — | — | US | disclosed |
| US-20090036659-A1 | METHOD OF DEUTERATING BENZYL-POSITION IN -O-BENZYL GROUP | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 2009-02-05 | — | — | US | disclosed |
| EP-1992605-A1 | METHOD OF DEUTERIZING BENZYL-POSITION IN -O-BENZYL GROUP | Wako Pure Chemical Industries, Ltd. (JP) | 2008-11-19 | — | — | EP | disclosed |
| US-20060106254-A1 | Method for producing hydroxylamine compound using platinum catalyst fixed on ion-exchange resin | FUJIFILM WAKO PURE CHEMICAL CORPORATION (JP) | 2006-05-18 | — | — | US | disclosed |
| EP-1593668-A1 | METHOD FOR PRODUCING HYDROXYLAMINE COMPOUND USING PLATINUM CATALYST FIXED ON ION EXCHANGE RESIN | Wako Pure Chemical Industries, Ltd. (JP) | 2005-11-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100113830-A1 | METHOD FOR PRODUCING ARYLHYDROXYLAMINE | PAH, APEH, HPD | MAPK1 3586/4885ALDH1A1 935/4885TAAR1 104/4885 |
| US-20060106254-A1 | Method for producing hydroxylamine compound using platinum catalyst fixed on ion-exchange resin | HNMT, HRH4, HRH3 | MAPK1 4442/4885ALDH1A1 2155/4885TAAR1 1646/4885 |
| US-20090036659-A1 | METHOD OF DEUTERATING BENZYL-POSITION IN -O-BENZYL GROUP | DBH, BRD4, BRD3 | MAPK1 3080/4885ALDH1A1 3409/4885TAAR1 3849/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.