Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DEPTOR | Q8TB45 | 1/20 | 0.37 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 3/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | CASP3 | P42574 | 1/20 | 0.31 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.31 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.31 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 4/20 | 0.31 |
| ▸ | HPGD | P15428 | 3/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL6618711 | 0.81 | LRRK2 (0.33) | HTTRAB9AKMT2ANPC1MEN1 | |
| Ammonia Solution, Strong SCHEMBL6618697 | 0.78 | MAPT (0.37) | TSHRALDH1A1HTTRAB9AKMT2A | |
| SCHEMBL922326 | 0.76 | DEPTOR (0.39) | DEPTORCYP1A1TSHRCYP1B1TDP1 | |
| SCHEMBL922327 | 0.76 | DEPTOR (0.39) | DEPTORCYP1A1TSHRCYP1B1TDP1 | |
| Ammonia Solution, Strong SCHEMBL6617540 | 0.74 | DEPTOR (0.41) | DEPTORALDH1A1RAB9AKMT2ANPC1 | |
| SCHEMBL922393 | 0.67 | DEPTOR (0.44) | DEPTORCYP1A1TSHRCYP1B1TDP1 | |
| SCHEMBL922391 | 0.67 | DEPTOR (0.44) | DEPTORCYP1A1TSHRCYP1B1TDP1 | |
| SCHEMBL6656042 | 0.62 | MAPT (0.42) | TSHRTDP1ALDH1A1HTTRAB9A | |
| SCHEMBL7695936 | 0.62 | MAPT (0.36) | TDP1ALDH1A1HTTRAB9AKMT2A | |
| SCHEMBL901064 | 0.61 | ALDH1A1 (0.41) | DEPTORCYP1A1TSHRCYP1B1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1450791-A1 | HYDRAZONOPYRAZOLE DERIVATIVES AND THEIR USE AS THERAPEUTICS | Kinetek Pharmaceuticals, Inc. (CA) | 2004-09-01 | — | — | EP | disclosed |
| WO-2003045379-A1 | HYDRAZONOPYRAZOLE DERIVATIVES AND THEIR USE AS THERAPEUTICS | KINETEK PHARMACEUTICALS, INC. (CA) | 2003-06-05 | — | — | WO | disclosed |