Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CFTR | P13569 | 1/20 | 0.33 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7695936 | 0.73 | MAPT (0.36) | MAPTKMT2AHPGDNPSR1TDP1 | |
| SCHEMBL5360787 | 0.72 | MAPT (0.36) | MAPTKMT2AHPGDNPSR1TDP1 | |
| SCHEMBL14889308 | 0.67 | ALDH1A1 (0.44) | MAPTKMT2AHPGDTDP1ALDH1A1 | |
| SCHEMBL4633787 | 0.65 | MAPT (0.44) | MAPTKMT2AHPGDALDH1A1LMNA | |
| SCHEMBL8718613 | 0.65 | MAPT (0.39) | MAPTKMT2AHPGDNPSR1ALDH1A1 | |
| SCHEMBL576916 | 0.64 | ALDH1A1 (0.47) | MAPTKMT2AHPGDTDP1ALDH1A1 | |
| SCHEMBL8809436 | 0.64 | MAPT (0.39) | MAPTKMT2AHPGDNPSR1ALDH1A1 | |
| Biphenyl SCHEMBL13739106 | 0.61 | ALDH1A1 (0.90) | MAPTTDP1ALDH1A1LMNAHTT | |
| Biphenyl SCHEMBL10906408 | 0.61 | ALDH1A1 (0.90) | MAPTTDP1ALDH1A1LMNAHTT | |
| Biphenyl SCHEMBL11128312 | 0.61 | ALDH1A1 (0.90) | MAPTTDP1ALDH1A1LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1372584-A1 | HAIR COLOURING COMPOSITIONS COMPRISING PYRAZOLONE DERIVATIVES AND THEIR USE | THE PROCTER & GAMBLE COMPANY (US) | 2004-01-02 | — | — | EP | claimed |
| WO-2002080871-A1 | HAIR COLOURING COMPOSITIONS COMPRISING PYRAZOLONE DERIVATIVES AND THEIR USE | THE PROCTER & GAMBLE COMPANY (US) | 2002-10-17 | — | — | WO | claimed |