Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 2/20 | 0.49 |
| ▸ | CTSK | P43235 | 1/20 | 0.49 |
| ▸ | PSEN1 | P49768 | 3/20 | 0.40 |
| ▸ | PSEN2 | P49810 | 3/20 | 0.40 |
| ▸ | APH1B | Q8WW43 | 3/20 | 0.40 |
| ▸ | NCSTN | Q92542 | 3/20 | 0.40 |
| ▸ | APH1A | Q96BI3 | 3/20 | 0.40 |
| ▸ | PSENEN | Q9NZ42 | 3/20 | 0.40 |
| ▸ | LDHB | P07195 | 2/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | F10 | P00742 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6620554 | 0.80 | CTSL (0.56) | CTSLCTSKPSEN1PSEN2APH1B | |
| SCHEMBL6621996 | 0.78 | CTSL (0.54) | CTSLCTSKPSEN1PSEN2APH1B | |
| SCHEMBL6621993 | 0.78 | CTSK (0.54) | CTSLCTSKPSEN1PSEN2APH1B | |
| Butanone SCHEMBL6621293 | 0.78 | FFAR1 (0.46) | CTSLCTSKCNR1F2F10 | |
| SCHEMBL1177543 | 0.77 | POLB (0.47) | POLBSYK | |
| SCHEMBL5249260 | 0.74 | CTSL (0.48) | CTSLCTSKCNR1CYP1A2POLB | |
| SCHEMBL29793885 | 0.74 | CTSL (0.48) | CTSLCTSKCNR1CYP1A2POLB | |
| SCHEMBL5216832 | 0.74 | CTSL (0.48) | CTSLCTSKCNR1CYP1A2POLB | |
| SCHEMBL30353435 | 0.74 | RXRA (0.54) | CTSLCTSKPSEN1PSEN2APH1B | |
| SCHEMBL9261215 | 0.74 | CTSK (0.50) | CTSLCTSKCNR1CYP1A2CTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1067894-A4 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORP (US) | 2004-09-08 | — | — | EP | claimed |
| EP-1067894-A2 | PROTEASE INHIBITORS | SmithKline Beecham Corporation (US) | 2001-01-17 | — | — | EP | claimed |
| WO-1999059526-A2 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 1999-11-25 | — | — | WO | claimed |