Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.44 |
| ▸ | CETP | P11597 | 1/20 | 0.42 |
| ▸ | NAPEPLD | Q6IQ20 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HTR3A | P46098 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14938330 | 0.78 | SIGMAR1 (0.39) | KMT2ASIGMAR1CETPNAPEPLDHTR2C | |
| SCHEMBL28856183 | 0.75 | SIGMAR1 (0.34) | KMT2ASIGMAR1MEN1 | |
| SCHEMBL29144839 | 0.74 | SIGMAR1 (0.44) | KMT2ASIGMAR1HTR2CSLC6A4SLC6A2 | |
| Acetic Acid SCHEMBL27373593 | 0.73 | SIGMAR1 (0.66) | KMT2ASIGMAR1SLC6A4SLC6A3OPRM1 | |
| SCHEMBL5521576 | 0.72 | MEN1 (0.41) | KMT2ASIGMAR1MEN1 | |
| SCHEMBL28199273 | 0.72 | SIGMAR1 (0.36) | SIGMAR1 | |
| SCHEMBL20897791 | 0.71 | MGLL (0.62) | KMT2ASIGMAR1MEN1 | |
| SCHEMBL5717885 | 0.71 | SIGMAR1 (0.45) | KMT2ASIGMAR1HTR2CHTR6ALDH1A1 | |
| SCHEMBL9690903 | 0.71 | CHRM2 (0.51) | HTR6ALDH1A1NPC1RAB9ATDP1 | |
| SCHEMBL27332317 | 0.71 | NPC1 (0.46) | KMT2ASIGMAR1SLC6A3ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1434763-A2 | BETA-LACTAMYL VASOPRESSIN V1A ANTAGONISTS | Serenix Pharmaceuticals, LLC (US) | 2004-07-07 | — | — | EP | disclosed |
| WO-2003031407-A2 | β-LACTAMYL VASOPRESSIN VlaANTAGONISTS | SERENIX PHARMACEUTICALS, LLC (US) | 2003-04-17 | — | — | WO | disclosed |