Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | MLNR | O43193 | 1/20 | 0.31 |
| ▸ | CHKA | P35790 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28199273 | 0.89 | SIGMAR1 (0.36) | SIGMAR1CHRM5CHRM3MLNR | |
| SCHEMBL5521576 | 0.82 | MEN1 (0.41) | SIGMAR1CHRM5CHRM3MLNRKMT2A | |
| SCHEMBL27618554 | 0.80 | SIGMAR1 (0.46) | SIGMAR1 | |
| SCHEMBL28199286 | 0.80 | POLB (0.41) | SIGMAR1KMT2AMEN1 | |
| SCHEMBL27583601 | 0.77 | CA14 (0.35) | SIGMAR1MLNR | |
| SCHEMBL6622116 | 0.75 | KMT2A (0.48) | SIGMAR1KMT2AMEN1 | |
| SCHEMBL27989613 | 0.72 | MAPT (0.35) | SIGMAR1 | |
| SCHEMBL28199271 | 0.71 | CA2 (0.38) | SIGMAR1CHRM5CHRM3CA2CA12 | |
| SCHEMBL9224877 | 0.71 | — | — | |
| SCHEMBL6632262 | 0.69 | SIGMAR1 (0.36) | SIGMAR1CHRM5CHRM3CA2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107698603-A | Thienopyrimidines, its preparation method, Pharmaceutical composition and its application | 厦门大学 | 2018-02-16 | — | — | CN | claimed |