Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.61 |
| ▸ | RECQL | P46063 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 4/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | POLB | P06746 | 3/20 | 0.58 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | DRD4 | P21917 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL962507 | 0.85 | ALDH1A1 (0.61) | ALDH1A1RECQLLMNAKMT2AMEN1 | |
| SCHEMBL15086506 | 0.79 | ALDH1A1 (0.78) | ALDH1A1RECQLLMNAKMT2AMEN1 | |
| SCHEMBL8354074 | 0.79 | MAPT (0.68) | ALDH1A1LMNAKMT2AMEN1KDM4E | |
| SCHEMBL8353854 | 0.78 | ALDH1A1 (0.66) | ALDH1A1LMNAKMT2AMEN1KDM4E | |
| Hydrochloric Acid SCHEMBL8351225 | 0.78 | MAPT (0.67) | ALDH1A1LMNAKMT2AMEN1KDM4E | |
| SCHEMBL8130534 | 0.78 | MAPK1 (0.56) | ALDH1A1LMNAKMT2AMEN1KDM4E | |
| Hydrochloric Acid SCHEMBL8356274 | 0.77 | ALDH1A1 (0.68) | ALDH1A1LMNAKMT2AMEN1KDM4E | |
| SCHEMBL7551929 | 0.77 | ALDH1A1 (0.62) | ALDH1A1RECQLLMNAKMT2AMEN1 | |
| SCHEMBL11280038 | 0.74 | HTR2A (0.62) | ALDH1A1LMNAKMT2AMEN1KDM4E | |
| SCHEMBL9425105 | 0.73 | LMNA (0.84) | ALDH1A1LMNAKMT2AMEN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1218352-B1 | BENZIMIDAZOLONE DERIVATIVES HAVING MIXED SEROTONINE AND DOPAMINE RECEPTORS AFFINITY | BOEHRINGER INGELHEIM ITALIA (IT) | 2004-05-12 | — | — | EP | disclosed |
| EP-1218352-A1 | BENZIMIDAZOLONE DERIVATIVES HAVING MIXED SEROTONINE AND DOPAMINE RECEPTORS AFFINITY | BOEHRINGER INGELHEIM ITALIA S.p.A. (IT) | 2002-07-03 | — | — | EP | disclosed |
| US-6281218-B1 | USEFUL IN THE TREATMENT OF CNS DISORDERS. | INGELHEIM ITALIA S.P.A. (IT) | 2001-08-28 | — | — | US | disclosed |
| WO-2001021593-A1 | NEW BENZIMIDAZOLONE DERIVATIVES HAVING MIXED SEROTONINE AND DOPAMINE RECEPTORS AFFINITY | BOEHRINGER INGELHEIM ITALIA S.P.A. (IT) | 2001-03-29 | — | — | WO | disclosed |