Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.62 |
| ▸ | RECQL | P46063 | 1/20 | 0.62 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15086506 | 0.80 | ALDH1A1 (0.78) | ALDH1A1RECQLLMNAMAPTKMT2A | |
| SCHEMBL6622383 | 0.77 | ALDH1A1 (0.61) | ALDH1A1RECQLGAALMNAMAPT | |
| SCHEMBL962507 | 0.76 | ALDH1A1 (0.61) | ALDH1A1RECQLGAALMNAMAPT | |
| SCHEMBL3435109 | 0.71 | MAPT (0.67) | ALDH1A1RECQLGAALMNAMAPT | |
| SCHEMBL11776133 | 0.70 | ALDH1A1 (0.69) | ALDH1A1RECQLGAAMAPTKMT2A | |
| SCHEMBL31159573 | 0.70 | MAPT (0.68) | ALDH1A1RECQLMAPTKMT2ARAB9A | |
| SCHEMBL31570127 | 0.70 | ALDH1A1 (0.69) | ALDH1A1RECQLGAAMAPTKMT2A | |
| SCHEMBL960290 | 0.70 | MAPT (0.68) | ALDH1A1RECQLMAPTKMT2ARAB9A | |
| SCHEMBL978809 | 0.69 | RAB9A (0.73) | ALDH1A1LMNAMAPTKMT2ARAB9A | |
| SCHEMBL978808 | 0.69 | RAB9A (0.73) | ALDH1A1LMNAMAPTKMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1218352-A1 | BENZIMIDAZOLONE DERIVATIVES HAVING MIXED SEROTONINE AND DOPAMINE RECEPTORS AFFINITY | BOEHRINGER INGELHEIM ITALIA S.p.A. (IT) | 2002-07-03 | — | — | EP | disclosed |
| WO-2001021593-A1 | NEW BENZIMIDAZOLONE DERIVATIVES HAVING MIXED SEROTONINE AND DOPAMINE RECEPTORS AFFINITY | BOEHRINGER INGELHEIM ITALIA S.P.A. (IT) | 2001-03-29 | — | — | WO | disclosed |