Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | C1R | P00736 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 9/20 | 0.50 |
| ▸ | RAB9A | P51151 | 9/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.50 |
| ▸ | PKM | P14618 | 5/20 | 0.50 |
| ▸ | TP53 | P04637 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3957488 | 0.82 | NPC1 (0.67) | C1RNPC1RAB9ASMN1; SMN2PKM | |
| SCHEMBL8367944 | 0.77 | NPC1 (0.55) | C1RNPC1RAB9ASMN1; SMN2PKM | |
| SCHEMBL13719127 | 0.73 | RAB9A (0.46) | C1RNPC1RAB9ASMN1; SMN2PKM | |
| SCHEMBL27578582 | 0.72 | RAB9A (0.69) | C1RNPC1RAB9ASMN1; SMN2PKM | |
| SCHEMBL14500973 | 0.72 | NPC1 (0.53) | C1RNPC1RAB9ASMN1; SMN2PKM | |
| SCHEMBL16552918 | 0.72 | ELANE (0.44) | — | |
| SCHEMBL4684542 | 0.71 | C1R (0.54) | C1RNPC1RAB9ASMN1; SMN2PKM | |
| SCHEMBL14500936 | 0.70 | NPC1 (0.54) | C1RNPC1RAB9ASMN1; SMN2PKM | |
| SCHEMBL1298859 | 0.70 | L3MBTL1 (0.40) | NPC1RAB9ASMN1; SMN2MAPTMEN1 | |
| SCHEMBL2429466 | 0.69 | ITGA4 (0.56) | C1RNPC1RAB9ASMN1; SMN2PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1448180-A1 | PARA-AMINO BENZOIC ACIDS AS INTEGRIN ANTAGONISTS | Bayer HealthCare AG (DE) | 2004-08-25 | — | — | EP | disclosed |
| WO-2003030889-A1 | PARA-AMINO BENZOIC ACIDS AS INTEGRIN ANTAGONISTS | BAYER HEALTHCARE AG (DE) | 2003-04-17 | — | — | WO | disclosed |