SCHEMBL662263

SCHEMBL662263

CC/C=C1\CC(C)OC1=O

nearest known ligand 0.45

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
DYRK1A Q13627 3/20 0.45
DYRK1B Q9Y463 3/20 0.45
CLK1 P49759 2/20 0.45
SMN1; SMN2 Q16637 1/20 0.43
PIK3CA P42336 1/20 0.39
DYRK2 Q92630 1/20 0.39
MAOB P27338 5/20 0.38
MAOA P21397 10/20 0.36
KDM4E B2RXH2 1/20 0.34
POLB P06746 1/20 0.34
MAPT P10636 1/20 0.34
PPARG P37231 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24934339 1.00 DYRK1A (0.45) DYRK1ADYRK1BCLK1SMN1; SMN2PIK3CA
SCHEMBL10186549 1.00 DYRK1A (0.45) DYRK1ADYRK1BCLK1SMN1; SMN2PIK3CA
SCHEMBL12676122 1.00 DYRK1A (0.45) DYRK1ADYRK1BCLK1SMN1; SMN2PIK3CA
SCHEMBL12675741 0.85 PPARG (0.45) DYRK1ADYRK1BCLK1SMN1; SMN2PIK3CA
SCHEMBL664822 0.85 PPARG (0.45) DYRK1ADYRK1BCLK1SMN1; SMN2PIK3CA
SCHEMBL9709390 0.85 PPARG (0.45) DYRK1ADYRK1BCLK1SMN1; SMN2PIK3CA
SCHEMBL20220599 0.82 DYRK1A (0.44) DYRK1ADYRK1BCLK1SMN1; SMN2PIK3CA
SCHEMBL5936319 0.82 PRKCA (0.44) DYRK1ADYRK1BCLK1SMN1; SMN2PIK3CA
SCHEMBL21895492 0.82 PRKCA (0.44) DYRK1ADYRK1BCLK1SMN1; SMN2PIK3CA
SCHEMBL663296 0.82 PRKCA (0.44) DYRK1ADYRK1BCLK1SMN1; SMN2PIK3CA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 223 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4074807-B1 COMPOSITIONS COMPRISING A FLUOROOLEFIN CHEMOURS CO FC LLC (US) 2025-07-09 EP disclosed
EP-3543310-B2 COMPOSITIONS COMPRISING HFC-1234YF AND HFC-32 CHEMOURS CO FC LLC (US) 2024-07-03 EP disclosed
EP-3299435-B1 METHOD OF PREPARING A COMPOSITION COMPRISING HFC-1234YF CHEMOURS CO FC LLC (US) 2024-06-26 EP disclosed
EP-2749623-B2 Method for replacing a high GWP refrigerant in a refrigeration, air-conditioning, or heat pump apparatus CHEMOURS CO FC LLC (US) 2024-02-21 EP disclosed
EP-3309233-B2 COMPOSITIONS COMPRISING HFC-1234YF AND HFC-152A CHEMOURS CO FC LLC (US) 2024-02-21 EP disclosed
US-20230265330-A1 COMPOSITIONS COMPRISING A FLUOROOLEFIN THE CHEMOURS COMPANY FC, LLC (US) 2023-08-24 US disclosed
US-11674067-B2 Compositions comprising a fluoroolefin THE CHEMOURS COMPANY FC, LLC (US) 2023-06-13 US disclosed
US-20230018245-A1 Skin Whitening Composition Containing Dihydro-5-Methylfuran-2(3h)-One Derivative EPI BIOTECH CO., LTD. (KR) 2023-01-19 US disclosed
US-20220389297-A1 COMPOSITIONS COMPRISING A FLUOROOLEFIN THE CHEMOURS COMPANY FC, LLC (US) 2022-12-08 US disclosed
US-20220389298-A1 COMPOSITIONS COMPRISING A FLUOROOLEFIN THE CHEMOURS COMPANY FC, LLC (US) 2022-12-08 US disclosed
US-20050156139-A1 1-Ethoxy-1,1,2,2,3,3,4,4,4,-nonafluorobutane refrigerant compositions comprising a fluoroether and uses thereof E. I. DU PONT DE NEMOURS AND COMPANY 2005-07-21 US disclosed
US-20050151113-A1 Hydrofluorocarbon refrigerant compositions and uses thereof E. I. DU PONT DE NEMOURS AND COMPANY 2005-07-14 US disclosed
US-20050151110-A1 Fluoroether refrigerant compositions and uses thereof E. I. DU PONT DE NEMOURS AND COMPANY 2005-07-14 US disclosed
US-20050151112-A1 1,1,1,2,2,3,3,4,4-Nonafluoro-4-methoxybutane refrigerant compositions comprising hydrofluorocarbon, and uses thereof E. I. DU PONT DE NEMOURS AND COMPANY 2005-07-14 US disclosed
US-20050151111-A1 1,1,1,3,3-Pentafluorobutane refrigerant or heat transfer fluid compositions comprising hydrofluorocarbon and uses thereof E. I. DU PONT DE NEMOURS AND COMPANY 2005-07-14 US disclosed
US-20050145822-A1 Refrigerant compositions comprising UV fluorescent dye and solubilizing agent E. I. DU PONT DE NEMOURS AND COMPANY 2005-07-07 US disclosed
US-20050127321-A1 Compositions containing lactone compatibilizers E. I. DU PONT DE NEMOURS AND COMPANY 2005-06-16 US disclosed
US-20050109978-A1 Refrigerant compositions comprising performance enhancing additives LECK THOMAS J (US) 2005-05-26 US disclosed
WO-2005014565-A2 CIS-3,5-DISUBSTITUTED-DIHYDRO-FURAN-2-ONES AND THE PREPARATION AND USE THEREOF E.I. DUPONT DE NEMOURS AND COMPANY (US) 2005-02-17 WO disclosed
US-6841088-B2 Fluorocarbon, oxygenated and non-oxygenated lubricant, and compatibilizer composition, and method for replacing refrigeration composition in a refrigeration system E. I. DU PONT DE NEMOURS AND COMPANY (US) 2005-01-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230018245-A1 Skin Whitening Composition Containing Dihydro-5-Methylfuran-2(3h)-One Derivative MC1R, MC5R, MITF DYRK1A 1465/4885DYRK1B 1376/4885CLK1 2260/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.