Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 2/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CTSV | O60911 | 4/20 | 0.35 |
| ▸ | CTSL | P07711 | 4/20 | 0.35 |
| ▸ | THRA | P10827 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5398175 | 0.82 | THRB (0.43) | MAPTMEN1KMT2ASGMS2NPC1 | |
| SCHEMBL8799741 | 0.81 | MEN1 (0.47) | MAPTMEN1KMT2ATHRBRORC | |
| SCHEMBL5404873 | 0.77 | POLB (0.38) | MAPTMEN1KMT2ASGMS2NPC1 | |
| SCHEMBL5391540 | 0.76 | POLB (0.39) | MAPTMEN1KMT2ASGMS2NPC1 | |
| SCHEMBL5401768 | 0.76 | THRB (0.44) | MAPTMEN1KMT2ASGMS2NPC1 | |
| SCHEMBL9960150 | 0.70 | POLB (0.48) | MAPTMEN1KMT2ASGMS2GLRA1 | |
| SCHEMBL5399271 | 0.69 | POLB (0.42) | MAPTMEN1KMT2ANPC1RAB9A | |
| SCHEMBL5404292 | 0.68 | THRB (0.43) | THRBRORCGLRA1THRA | |
| SCHEMBL5397627 | 0.68 | THRB (0.43) | SGMS2THRBRORCGLRA1THRA | |
| SCHEMBL5401387 | 0.68 | THRB (0.50) | THRBTHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1471049-A1 | NOVEL THYROID HORMONE RECEPTOR LIGAND, MEDICINAL COMPOSITIONS CONTAINING THE SAME AND USE THEREOF | Kissei Pharmaceutical Co., Ltd. (JP) | 2004-10-27 | — | — | EP | disclosed |