Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.33 |
| ▸ | RPS6KA1 | Q15418 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6702187 | 0.77 | CCR3 (0.42) | — | |
| SCHEMBL5762925 | 0.76 | MAPT (0.36) | MEN1KMT2AMAPTPOLB | |
| SCHEMBL6623481 | 0.76 | MAPT (0.36) | ALDH1A1CYP1A2MEN1KMT2AMAPT | |
| SCHEMBL5761023 | 0.76 | MAPT (0.38) | ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL5762210 | 0.75 | MAPT (0.35) | MEN1KMT2AMAPT | |
| SCHEMBL6637614 | 0.71 | NTRK1 (0.42) | KDM2BMEN1KMT2AIDO1 | |
| SCHEMBL6622074 | 0.71 | SCN9A (0.37) | ALDH1A1CYP1A2MEN1KMT2AMAPT | |
| SCHEMBL6637339 | 0.65 | RAB9A (0.40) | MAPK1ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL6620915 | 0.64 | CYP3A4 (0.43) | MEN1KMT2AMAPT | |
| Hydrochloric Acid SCHEMBL5341112 | 0.64 | KDM2B (0.42) | ALDH1A1KDM2BMEN1KMT2AKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1487435-A1 | AZETIDINE DERIVATIVES AS CCR-3 RECEPTOR ANTAGONISTS | Novartis AG (CH) | 2004-12-22 | — | — | EP | disclosed |
| WO-2003077907-A1 | AZETIDINE DERIVATIVES AS CCR-3 RECEPTOR ANTAGONISTS | NOVARTIS AG (CH) | 2003-09-25 | — | — | WO | disclosed |