Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 6/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 3/20 | 0.38 |
| ▸ | HTR2A | P28223 | 3/20 | 0.38 |
| ▸ | HTR1A | P08908 | 2/20 | 0.36 |
| ▸ | HTR7 | P34969 | 2/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6622794 | 0.99 | PARP1 (0.44) | PARP1ACHEHTR2CHTR2AHTR1A | |
| SCHEMBL6625270 | 0.85 | HTR1A (0.43) | PARP1HTR2CHTR2AHTR1AHTR7 | |
| SCHEMBL6624045 | 0.80 | PARP1 (0.48) | PARP1HTR2CHTR2ADRD2 | |
| SCHEMBL6622880 | 0.80 | PARP1 (0.48) | PARP1HTR2CHTR2ADRD2 | |
| SCHEMBL6625091 | 0.80 | MAPT (0.39) | PARP1ACHE | |
| SCHEMBL6624826 | 0.79 | PARP1 (0.45) | PARP1HTR2CHTR2ADRD2 | |
| Hydrochloric Acid SCHEMBL6624304 | 0.79 | MAPT (0.38) | PARP1ACHE | |
| Hydrochloric Acid SCHEMBL6626987 | 0.78 | PARP1 (0.47) | PARP1HTR2CHTR2ADRD2 | |
| SCHEMBL6625432 | 0.75 | PARP1 (0.44) | PARP1HTR2CHTR2ADRD2 | |
| SCHEMBL6624741 | 0.74 | PARP1 (0.43) | PARP1HTR2CHTR2ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0858996-B1 | NERVE CELL PROTECTIVE AGENTS | MOCHIDA PHARM CO LTD (JP) | 2004-10-27 | — | — | EP | disclosed |
| US-6040331-A | Nerve cell protective agents | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2000-03-21 | — | — | US | disclosed |
| EP-0858996-A1 | NERVE CELL PROTECTIVE AGENTS | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1998-08-19 | — | — | EP | disclosed |