Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.38 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL951581 | 0.83 | TSHR (0.46) | ADRA1AADRA1BLMNAALDH1A1EGFR | |
| SCHEMBL7675373 | 0.81 | ALDH1A1 (0.42) | ADRA1AADRA1BLMNAALDH1A1EGFR | |
| SCHEMBL3499475 | 0.81 | LMNA (0.44) | ADRA1AADRA1BLMNAALDH1A1EGFR | |
| SCHEMBL27670092 | 0.80 | ALDH1A1 (0.41) | ADRA1AADRA1BLMNAALDH1A1HIF1A | |
| SCHEMBL319240 | 0.80 | ALDH1A1 (0.45) | ADRA1AADRA1BLMNAALDH1A1EGFR | |
| Hydrochloric Acid SCHEMBL29024518 | 0.80 | TSHR (0.43) | ADRA1AADRA1BLMNAALDH1A1EGFR | |
| SCHEMBL30736662 | 0.80 | ALDH1A1 (0.45) | ADRA1AADRA1BLMNAALDH1A1EGFR | |
| SCHEMBL16940008 | 0.80 | ALDH1A1 (0.41) | ADRA1AADRA1BLMNAALDH1A1EGFR | |
| SCHEMBL4838670 | 0.80 | ALDH1A1 (0.41) | ADRA1AADRA1BLMNAALDH1A1EGFR | |
| SCHEMBL5984166 | 0.79 | BCAT2 (0.49) | ADRA1AADRA1BLMNAALDH1A1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0986384-A4 | INHIBITORS OF PROTEIN ISOPRENYL TRANSFERASES | UNIV PITTSBURGH (US) | 2004-09-15 | — | — | EP | disclosed |
| EP-0986384-A1 | INHIBITORS OF PROTEIN ISOPRENYL TRANSFERASES | UNIVERSITY OF PITTSBURGH (US) | 2000-03-22 | — | — | EP | disclosed |
| WO-1998050029-A1 | INHIBITORS OF PROTEIN ISOPRENYL TRANSFERASES | UNIVERSITY OF PITTSBURGH (US) | 1998-11-12 | — | — | WO | disclosed |