Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 5/20 | 0.44 |
| ▸ | CA9 | Q16790 | 5/20 | 0.44 |
| ▸ | CA12 | O43570 | 3/20 | 0.44 |
| ▸ | CA1 | P00915 | 3/20 | 0.44 |
| ▸ | IKBKB | O14920 | 1/20 | 0.43 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.40 |
| ▸ | CKS1B | P61024 | 1/20 | 0.36 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.36 |
| ▸ | PTPRC | P08575 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.35 |
| ▸ | IDH2 | P48735 | 1/20 | 0.35 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6681642 | 0.87 | LRRK2 (0.44) | CA2CA9CA12CA1IKBKB | |
| SCHEMBL27997605 | 0.86 | CA2 (0.43) | CA2CA9CA12CA1ENPP3 | |
| SCHEMBL6623867 | 0.84 | PDPK1 (0.49) | CA2CA9CA12CA1ENPP3 | |
| SCHEMBL6624144 | 0.78 | PTPRC (0.43) | CA2CA9CA12CA1IKBKB | |
| SCHEMBL20899926 | 0.78 | CA2 (0.45) | CA2CA9CA12CA1ENPP3 | |
| SCHEMBL20899969 | 0.76 | CA2 (0.51) | CA2CA9CA12CA1NPC1 | |
| SCHEMBL31345785 | 0.73 | LOXL2 (0.56) | CA2CA9CA12CA1ENPP3 | |
| SCHEMBL5693321 | 0.72 | CA2 (0.41) | CA2CA9CA12CA1ENPP3 | |
| SCHEMBL27944286 | 0.71 | CA2 (0.55) | CA2CA9CA12CA1ENPP3 | |
| Hydrochloric Acid SCHEMBL20899879 | 0.71 | CA2 (0.40) | CA2CA9CA12CA1ENPP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1461325-A1 | INHIBITORS OF 11-BETA-HYDROXY STEROID DEHYDROGENASE TYPE 1 | BIOVITRUM AB (SE) | 2004-09-29 | — | — | EP | disclosed |
| WO-2003043999-A1 | INHIBITORS OF 11-BETA-HYDROXY STEROID DEHYDROGENASE TYPE 1 | BIOVITRUM AB (SE) | 2003-05-30 | — | — | WO | disclosed |