Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 17/20 | 0.37 |
| ▸ | THRA | P10827 | 3/20 | 0.36 |
| ▸ | THRB | P10828 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6624275 | 0.89 | ALDH1A1 (0.33) | ERN1THRATHRB | |
| SCHEMBL5401337 | 0.79 | ERN1 (0.44) | ERN1THRATHRB | |
| SCHEMBL5394328 | 0.74 | MAPT (0.44) | ERN1 | |
| SCHEMBL5391479 | 0.72 | THRB (0.54) | THRATHRB | |
| SCHEMBL5397899 | 0.71 | THRB (0.49) | THRATHRB | |
| SCHEMBL5401756 | 0.69 | HTR7 (0.45) | THRB | |
| SCHEMBL5396348 | 0.68 | POLB (0.41) | THRATHRB | |
| SCHEMBL5397581 | 0.68 | MAPT (0.46) | THRATHRB | |
| SCHEMBL5402710 | 0.67 | CYP19A1 (0.44) | — | |
| SCHEMBL5402707 | 0.67 | CYP19A1 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1471049-A1 | NOVEL THYROID HORMONE RECEPTOR LIGAND, MEDICINAL COMPOSITIONS CONTAINING THE SAME AND USE THEREOF | Kissei Pharmaceutical Co., Ltd. (JP) | 2004-10-27 | — | — | EP | disclosed |