Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | KDM5A | P29375 | 1/20 | 0.44 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.44 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28790796 | 0.86 | KDM4E (0.62) | KDM4EALDH1A1HSD17B10HPGDHTT | |
| SCHEMBL9205154 | 0.80 | KDM5A (0.54) | KDM4EALDH1A1HSD17B10HPGDHTT | |
| SCHEMBL8176000 | 0.80 | ALDH1A1 (0.53) | ALDH1A1HSD17B10HPGDHTTPOLB | |
| SCHEMBL28790818 | 0.78 | KDM4E (0.63) | KDM4EALDH1A1HSD17B10HPGDHTT | |
| SCHEMBL6623749 | 0.77 | KDM5A (0.45) | KDM4EALDH1A1HSD17B10HPGDPOLB | |
| SCHEMBL8184450 | 0.76 | KDM4E (0.49) | KDM4EALDH1A1HSD17B10HPGDPOLB | |
| SCHEMBL8175915 | 0.74 | PDE4A (0.54) | KDM4EALDH1A1HSD17B10HPGDHTT | |
| SCHEMBL8188714 | 0.72 | KDM4E (0.47) | KDM4EALDH1A1HSD17B10HPGDHTT | |
| SCHEMBL6629334 | 0.72 | KDM4E (0.59) | KDM4EALDH1A1HSD17B10HPGDHTT | |
| SCHEMBL6627418 | 0.72 | KDM4E (0.56) | KDM4EALDH1A1HSD17B10HPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0976754-B1 | REMEDIES/PREVENTIVES FOR RESPIRATORY DISEASES | POLA CHEM IND INC (JP) | 2004-07-14 | — | — | EP | disclosed |
| US-6329382-B1 | TREATMENT OF RESPIRATORY DISEASES | POLA CHEMICAL INDUSTRIES, INC. (JP) | 2001-12-11 | — | — | US | disclosed |
| EP-0976754-A1 | REMEDIES/PREVENTIVES FOR RESPIRATORY DISEASES | POLA CHEMICAL INDUSTRIES, INC. (JP) | 2000-02-02 | — | — | EP | disclosed |