Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.73 |
| ▸ | MEN1 | O00255 | 5/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.73 |
| ▸ | MAPT | P10636 | 3/20 | 0.73 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.73 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.73 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.73 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.73 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.73 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.73 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.73 |
| ▸ | HPGD | P15428 | 4/20 | 0.72 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.70 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 4/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3915795 | 0.82 | ALDH1A1 (0.70) | ALDH1A1MEN1KMT2AMAPTCYP1A2 | |
| SCHEMBL6624465 | 0.82 | ALDH1A1 (0.79) | ALDH1A1MEN1KMT2AMAPTCYP1A2 | |
| SCHEMBL312905 | 0.81 | ALDH1A1 (0.52) | ALDH1A1MEN1KMT2AMAPTCYP1A2 | |
| SCHEMBL14927290 | 0.81 | ALDH1A1 (0.67) | ALDH1A1MEN1KMT2AMAPTCYP1A2 | |
| SCHEMBL9834670 | 0.79 | ALDH1A1 (0.59) | ALDH1A1MEN1KMT2AMAPTCYP1A2 | |
| SCHEMBL3973235 | 0.78 | ALDH1A1 (0.65) | ALDH1A1MEN1KMT2AMAPTCYP1A2 | |
| SCHEMBL8507040 | 0.78 | ALDH1A1 (0.63) | ALDH1A1MEN1KMT2AMAPTCYP1A2 | |
| SCHEMBL14927266 | 0.78 | ALDH1A1 (0.63) | ALDH1A1MEN1KMT2AMAPTCYP1A2 | |
| SCHEMBL898645 | 0.78 | ALDH1A1 (0.63) | ALDH1A1MEN1KMT2AMAPTCYP1A2 | |
| SCHEMBL8536799 | 0.76 | NPC1 (0.58) | ALDH1A1MEN1KMT2AMAPTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8093428-B2 | Synthesis of quaternary salt compounds | JANSSEN PHARMACEUTICA N.V. (BE) | 2012-01-10 | — | — | US | disclosed |
| US-7799824-B2 | Quaternary salt CCR2 antagonists | ORAPHARMA, INC. (US) | 2010-09-21 | — | — | US | disclosed |
| US-20060293379-A1 | Quaternary salt CCR2 antagonists | KENVUE BRANDS LLC | 2006-12-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060293379-A1 | Quaternary salt CCR2 antagonists | CCR2, CCR1, CXCR2 | ALDH1A1 1250/4885MEN1 4686/4885KMT2A 1470/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.