Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 14/20 | 0.43 |
| ▸ | MAOA | P21397 | 13/20 | 0.43 |
| ▸ | MAOB | P27338 | 13/20 | 0.43 |
| ▸ | CTSC | P53634 | 4/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL669219 | 0.86 | MAPK1 (0.44) | KDM1AMAOAMAOBCTSCCTSL | |
| SCHEMBL15960825 | 0.80 | MAPT (0.43) | KDM1AMAOAMAOBCTSCCTSL | |
| SCHEMBL11880622 | 0.78 | NPC1 (0.41) | KDM1AMAOAMAOBCTSCCTSL | |
| SCHEMBL11209553 | 0.76 | SMN1; SMN2 (0.50) | CTSCCYP2C19 | |
| SCHEMBL10073856 | 0.76 | RORC (0.42) | KDM1AMAOAMAOBCTSCCHRM1 | |
| SCHEMBL307974 | 0.73 | KDM1A (0.48) | KDM1AMAOAMAOBMAPK1CYP2C19 | |
| SCHEMBL6628664 | 0.72 | CHRM1 (0.56) | KDM1AMAOAMAOBMAPK1CYP2C19 | |
| SCHEMBL903405 | 0.72 | KDM1A (0.52) | KDM1AMAOAMAOB | |
| SCHEMBL901505 | 0.72 | KDM1A (0.52) | KDM1AMAOAMAOB | |
| SCHEMBL12498974 | 0.72 | KDM1A (0.47) | KDM1AMAOAMAOBMAPK1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1377589-A1 | OXAZOLYL-PYRAZOLE DERIVATIVES AS KINASE INHIBITORS | Pharmacia Italia S.p.A. (IT) | 2004-01-07 | — | — | EP | claimed |
| WO-2002062804-A1 | OXAZOLYL-PYRAZOLE DERIVATIVES AS KINASE INHIBITORS | PHARMACIA ITALIA S.P.A. (IT) | 2002-08-15 | — | — | WO | claimed |