Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GFER | P55789 | 1/20 | 0.70 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.68 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.68 |
| ▸ | CASP1 | P29466 | 1/20 | 0.68 |
| ▸ | CASP7 | P55210 | 1/20 | 0.68 |
| ▸ | MAPT | P10636 | 6/20 | 0.56 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | PIM1 | P11309 | 1/20 | 0.46 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.46 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | IKBKB | O14920 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6683973 | 0.99 | GFER (0.68) | GFERALOX15MAPK1HSD17B10CASP1 | |
| SCHEMBL30561947 | 0.84 | NISCH (0.57) | GFERALOX15MAPK1HSD17B10CASP1 | |
| SCHEMBL12764968 | 0.84 | GFER (0.49) | GFERALOX15MAPK1HSD17B10CASP1 | |
| SCHEMBL29264060 | 0.84 | NISCH (0.57) | GFERALOX15MAPK1HSD17B10CASP1 | |
| SCHEMBL3941869 | 0.82 | GFER (1.00) | GFERALOX15MAPK1HSD17B10CASP1 | |
| SCHEMBL30317424 | 0.82 | GFER (1.00) | GFERALOX15MAPK1HSD17B10CASP1 | |
| SCHEMBL12764963 | 0.82 | GFER (0.47) | GFERALOX15MAPK1HSD17B10CASP1 | |
| SCHEMBL4586298 | 0.81 | GFER (0.76) | GFERALOX15MAPK1HSD17B10CASP1 | |
| SCHEMBL150478 | 0.81 | ALOX15 (1.00) | GFERALOX15MAPK1HSD17B10CASP1 | |
| SCHEMBL6683286 | 0.81 | GFER (0.97) | GFERALOX15MAPK1HSD17B10CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004063156-A1 | NOVEL INDOLE DERIVATES AS FABP-4 INHIBITORS | BIOVITRUM AB (SE) | 2004-07-29 | — | — | WO | claimed |
| US-20230331673-A1 | COMPOSITION OF COMPOUNDS THAT MODULATE CELL METABOLISM AND METHODS OF USE | CRESCENTA BIOSCIENCES (US) | 2023-10-19 | — | — | US | disclosed |
| US-20230331673-A1 | COMPOSITION OF COMPOUNDS THAT MODULATE CELL METABOLISM AND METHODS OF USE | CRESCENTA BIOSCIENCES (US) | 2023-10-19 | — | — | US | disclosed |
| US-20230255933-A1 | ANTIVIRAL USE OF FABP4 MODULATING COMPOUNDS | CRESCENTA BIOSCIENCES (US) | 2023-08-17 | — | — | US | disclosed |
| US-20230241025-A1 | ANTIVIRAL USE OF FABP4 MODULATING COMPOUNDS | CRESCENTA BIOSCIENCES (US) | 2023-08-03 | — | — | US | disclosed |
| WO-2022010951-A1 | ANTIVIRAL USE OF FABP4 MODULATING COMPOUNDS | CRESCENTA BIOSCIENCES (US) | 2022-01-13 | — | — | WO | disclosed |
| US-20220002243-A1 | NOVEL CELL METABOLISM MODULATING COMPOUNDS AND USES THEREOF | CRESCENTA BIOSCIENCES (US) | 2022-01-06 | — | — | US | disclosed |
| WO-2021263246-A1 | NOVEL CELL METABOLISM MODULATING COMPOUNDS AND USES THEREOF | CRESCENTA BIOSCIENCES (US) | 2021-12-30 | — | — | WO | disclosed |
| US-8080566-B1 | Carbazole inhibitors of histamine receptors for the treatment of disease | KALYPSYS, INC (US) | 2011-12-20 | — | — | US | disclosed |
| US-8080566-B1 | Carbazole inhibitors of histamine receptors for the treatment of disease | KALYPSYS, INC (US) | 2011-12-20 | — | — | US | disclosed |
| US-8080566-B1 | Carbazole inhibitors of histamine receptors for the treatment of disease | KALYPSYS, INC (US) | 2011-12-20 | — | — | US | disclosed |
| EP-0831094-B1 | FUSED POLYCYCLIC HETEROCYCLE DERIVATIVES | EISAI CO LTD (JP) | 2004-12-08 | — | — | EP | disclosed |
| WO-2004063156-A1 | NOVEL INDOLE DERIVATES AS FABP-4 INHIBITORS | BIOVITRUM AB (SE) | 2004-07-29 | — | — | WO | disclosed |
| US-5952335-A | ANTITUMOR AGENTS | EISAI CO., LTD. (JP) | 1999-09-14 | — | — | US | disclosed |
| EP-0831094-A1 | FUSED POLYCYCLIC HETEROCYCLE DERIVATIVES | Eisai Co., Ltd. (JP) | 1998-03-25 | — | — | EP | disclosed |
| US-4057640-A | ANTIINFLAMMATORY | SCHERING AKTIENGESELLSCHAFT (DT) | 1977-11-08 | — | — | US | disclosed |
| US-3956295-A | ANTIINFLAMMATORY | SCHERING AKTIENGESELLSCHAFT (DT) | 1976-05-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220002243-A1 | NOVEL CELL METABOLISM MODULATING COMPOUNDS AND USES THEREOF | FABP4, FABP1, FABP3 | GFER 3646/4885ALOX15 635/4885MAPK1 3233/4885 |
| US-20230241025-A1 | ANTIVIRAL USE OF FABP4 MODULATING COMPOUNDS | FABP1, FABP4, FABP5 | GFER 3964/4885ALOX15 1181/4885MAPK1 4418/4885 |
| US-20230331673-A1 | COMPOSITION OF COMPOUNDS THAT MODULATE CELL METABOLISM AND METHODS OF USE | FABP4, FABP1, FABP3 | GFER 3962/4885ALOX15 722/4885MAPK1 3585/4885 |
| US-20230255933-A1 | ANTIVIRAL USE OF FABP4 MODULATING COMPOUNDS | FABP1, FABP4, FABP5 | GFER 3969/4885ALOX15 847/4885MAPK1 4441/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.