Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | GPR3 | P46089 | 1/20 | 0.32 |
| ▸ | BIRC5 | O15392 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | HTR6 | P50406 | 2/20 | 0.31 |
| ▸ | HTR1D | P28221 | 1/20 | 0.31 |
| ▸ | PER2 | O15055 | 1/20 | 0.31 |
| ▸ | CRY1 | Q16526 | 1/20 | 0.31 |
| ▸ | CRY2 | Q49AN0 | 1/20 | 0.31 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6626507 | 0.78 | KDM4E (0.43) | KDM4EL3MBTL1SLC6A2HTR2AHTR2C | |
| SCHEMBL3365470 | 0.74 | SLC6A2 (0.58) | SLC6A2HTR2AHTR2CBIRC5 | |
| SCHEMBL13956890 | 0.74 | KDM4E (0.60) | KDM4EATML3MBTL1GPR3POLB | |
| SCHEMBL30320243 | 0.71 | KDM4E (0.56) | KDM4EATML3MBTL1POLB | |
| SCHEMBL274318 | 0.71 | KDM4E (0.56) | KDM4EATML3MBTL1POLB | |
| SCHEMBL12200637 | 0.71 | KDM4E (0.56) | KDM4EATML3MBTL1GPR3POLB | |
| SCHEMBL11921965 | 0.70 | L3MBTL1 (0.67) | KDM4EATML3MBTL1GPR3POLB | |
| SCHEMBL11921992 | 0.70 | L3MBTL1 (0.67) | KDM4EATML3MBTL1GPR3POLB | |
| SCHEMBL16409588 | 0.70 | KDM4E (0.50) | KDM4EATML3MBTL1POLB | |
| SCHEMBL16409623 | 0.70 | KDM4E (0.50) | KDM4EATML3MBTL1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1035114-B1 | Processes for the preparation of nitrogen-heterocyclic compounds | TOSOH CORP (JP) | 2004-11-24 | — | — | EP | disclosed |
| US-6346621-B1 | INDOLE OR QUINOLINE COMPOUNDS SUBSTITUTED WITH AMINO COMPOUNDS ON NITROGEN | TOSOH CORPORATION (JP) | 2002-02-12 | — | — | US | disclosed |
| EP-1035114-A2 | Nitrogen-heterocyclic compounds and process for production thereof | TOSOH CORPORATION (JP) | 2000-09-13 | — | — | EP | disclosed |