Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 2/20 | 0.33 |
| ▸ | IDH1 | O75874 | 2/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.30 |
| ▸ | QPCT | Q16769 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6607697 | 1.00 | STING1 (0.33) | STING1IDH1ADRA1AARQPCT | |
| SCHEMBL6607557 | 0.88 | IDH1 (0.37) | STING1IDH1QPCT | |
| SCHEMBL6625580 | 0.88 | IDH1 (0.37) | STING1IDH1QPCT | |
| SCHEMBL6622011 | 0.82 | IDH1 (0.37) | STING1IDH1 | |
| SCHEMBL6773589 | 0.77 | F10 (0.46) | — | |
| SCHEMBL6607861 | 0.77 | F10 (0.46) | — | |
| SCHEMBL6679851 | 0.70 | MAOA (0.56) | — | |
| SCHEMBL6679857 | 0.70 | MAOA (0.56) | — | |
| SCHEMBL17287889 | 0.69 | HSP90AA1 (0.42) | IDH1ADRA1A | |
| SCHEMBL29950062 | 0.67 | NOTUM (0.41) | IDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1448536-A1 | CYCLOPROPYL-CONTAINING OXAZOLIDINONE ANTIBIOTICS AND DERIVATIVES THEREOF | Merck & Co., Inc. (US) | 2004-08-25 | — | — | EP | disclosed |
| WO-2003048136-A1 | CYCLOPROPYL HEXANE CONTAINING OXAZOLIDINONE ANTIBIOTICS AND DERIVATIVES THEREOF | MERCK & CO., INC. (US) | 2003-06-12 | — | — | WO | disclosed |