Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.44 |
| ▸ | SIRT6 | Q8N6T7 | 2/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | IDE | P14735 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6625012 | 0.86 | CNR1 (0.46) | MAPTGAAALDH1A1HPGDKMT2A | |
| SCHEMBL6623977 | 0.85 | MGAT2 (0.40) | MAPTKDM4EGAAALDH1A1CRBN | |
| SCHEMBL6628115 | 0.85 | CNR1 (0.49) | MAPTKDM4EAKR1C3ALDH1A1HPGD | |
| SCHEMBL6624454 | 0.85 | HTT (0.42) | MAPTKDM4EGAAALDH1A1POLB | |
| SCHEMBL6624722 | 0.85 | HTR1A (0.47) | MAPTKDM4EGAAAKR1C3ALDH1A1 | |
| SCHEMBL6625246 | 0.85 | HTT (0.49) | MAPTGAAALDH1A1KMT2ATDP1 | |
| SCHEMBL6628156 | 0.83 | NPC1 (0.42) | MAPTKDM4EGAAALDH1A1HPGD | |
| SCHEMBL6629939 | 0.83 | MAPT (0.50) | MAPTKDM4EGAAAKR1C3ALDH1A1 | |
| SCHEMBL6626698 | 0.81 | KMT2A (0.43) | MAPTKDM4EGAAALDH1A1POLB | |
| SCHEMBL6626057 | 0.81 | MAPT (0.48) | MAPTKDM4EGAAALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1373219-A1 | THIOHYDANTOINS AND USE THEREOF FOR TREATING DIABETES | LABORATOIRES FOURNIER S.A. (FR) | 2004-01-02 | — | — | EP | disclosed |
| WO-2002081453-A1 | THIOHYDANTOINS AND USE THEREOF FOR TREATING DIABETES | LABORATOIRES FOURNIER SA (FR) | 2002-10-17 | — | — | WO | disclosed |