Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.43 |
| ▸ | MEN1 | O00255 | 5/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 7/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
| ▸ | MGAT2 | Q10469 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6629939 | 0.88 | MAPT (0.50) | KMT2AMEN1ALDH1A1MAPTKDM4E | |
| SCHEMBL6626057 | 0.85 | MAPT (0.48) | KMT2AMEN1TSHRALDH1A1POLB | |
| SCHEMBL6625012 | 0.85 | CNR1 (0.46) | KMT2AMEN1TSHRALDH1A1MDM2 | |
| SCHEMBL6624454 | 0.84 | HTT (0.42) | KMT2AMEN1ALDH1A1POLBMAPT | |
| SCHEMBL6624722 | 0.84 | HTR1A (0.47) | KMT2AMEN1ALDH1A1POLBMAPT | |
| SCHEMBL6623977 | 0.84 | MGAT2 (0.40) | KMT2AMEN1TSHRALDH1A1MAPT | |
| SCHEMBL6628115 | 0.84 | CNR1 (0.49) | KMT2AMEN1TSHRALDH1A1MAPT | |
| SCHEMBL6625246 | 0.83 | HTT (0.49) | KMT2AMEN1TSHRALDH1A1MAPT | |
| SCHEMBL6628156 | 0.82 | NPC1 (0.42) | KMT2AMEN1TSHRALDH1A1MAPT | |
| SCHEMBL6625449 | 0.81 | MAPT (0.47) | KMT2AMEN1ALDH1A1POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1373219-A1 | THIOHYDANTOINS AND USE THEREOF FOR TREATING DIABETES | LABORATOIRES FOURNIER S.A. (FR) | 2004-01-02 | — | — | EP | disclosed |
| WO-2002081453-A1 | THIOHYDANTOINS AND USE THEREOF FOR TREATING DIABETES | LABORATOIRES FOURNIER SA (FR) | 2002-10-17 | — | — | WO | disclosed |