Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.72 |
| ▸ | MEN1 | O00255 | 5/20 | 0.72 |
| ▸ | LMNA | P02545 | 2/20 | 0.72 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.72 |
| ▸ | GAA | P10253 | 2/20 | 0.67 |
| ▸ | TP53 | P04637 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 2/20 | 0.63 |
| ▸ | HTR1E | P28566 | 1/20 | 0.63 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.63 |
| ▸ | CRHBP | P24387 | 1/20 | 0.60 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | MITF | O75030 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7748974 | 0.82 | POLB (0.66) | KMT2AMEN1LMNAL3MBTL1GAA | |
| SCHEMBL17365594 | 0.82 | POLB (0.66) | KMT2AMEN1LMNAL3MBTL1GAA | |
| SCHEMBL28168807 | 0.81 | KMT2A (0.56) | KMT2AMEN1LMNAL3MBTL1GAA | |
| SCHEMBL27798641 | 0.81 | KMT2A (0.56) | KMT2AMEN1LMNAL3MBTL1GAA | |
| SCHEMBL15456844 | 0.79 | L3MBTL1 (0.77) | KMT2AMEN1LMNAL3MBTL1GAA | |
| SCHEMBL16307627 | 0.78 | MAPT (0.63) | KMT2AMEN1LMNAGAAMAPT | |
| Acetanilide SCHEMBL27366940 | 0.78 | KMT2A (0.69) | KMT2AMEN1LMNAL3MBTL1GAA | |
| SCHEMBL6918119 | 0.78 | MAPT (0.70) | KMT2AMEN1LMNAGAAMAPT | |
| SCHEMBL29206349 | 0.78 | MEN1 (0.59) | KMT2AMEN1LMNAL3MBTL1GAA | |
| SCHEMBL29206352 | 0.78 | MEN1 (0.59) | KMT2AMEN1LMNAL3MBTL1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1377589-A1 | OXAZOLYL-PYRAZOLE DERIVATIVES AS KINASE INHIBITORS | Pharmacia Italia S.p.A. (IT) | 2004-01-07 | — | — | EP | claimed |
| WO-2002062804-A1 | OXAZOLYL-PYRAZOLE DERIVATIVES AS KINASE INHIBITORS | PHARMACIA ITALIA S.P.A. (IT) | 2002-08-15 | — | — | WO | claimed |