Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CASP6 | P55212 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | PYGL | P06737 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7310148 | 0.74 | PYGL (0.43) | L3MBTL1KMT2APYGL | |
| SCHEMBL6627705 | 0.74 | ADH1A (0.37) | L3MBTL1 | |
| SCHEMBL22346246 | 0.74 | SMN1; SMN2 (0.47) | ALDH1A1L3MBTL1 | |
| SCHEMBL163813 | 0.74 | SMN1; SMN2 (0.47) | ALDH1A1L3MBTL1 | |
| SCHEMBL25311355 | 0.73 | TDP1 (0.50) | ALDH1A1L3MBTL1TDP1LMNAKMT2A | |
| SCHEMBL26914635 | 0.73 | TDP1 (0.50) | ALDH1A1L3MBTL1TDP1LMNAKMT2A | |
| Cyclohexane SCHEMBL28249403 | 0.73 | TDP1 (0.50) | ALDH1A1L3MBTL1TDP1LMNAKMT2A | |
| SCHEMBL2779505 | 0.73 | TDP1 (0.50) | ALDH1A1L3MBTL1TDP1LMNAKMT2A | |
| SCHEMBL9134377 | 0.73 | TDP1 (0.50) | ALDH1A1L3MBTL1TDP1LMNAKMT2A | |
| SCHEMBL18797 | 0.73 | TDP1 (0.50) | ALDH1A1L3MBTL1TDP1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0986384-A4 | INHIBITORS OF PROTEIN ISOPRENYL TRANSFERASES | UNIV PITTSBURGH (US) | 2004-09-15 | — | — | EP | disclosed |
| EP-0986384-A1 | INHIBITORS OF PROTEIN ISOPRENYL TRANSFERASES | UNIVERSITY OF PITTSBURGH (US) | 2000-03-22 | — | — | EP | disclosed |
| WO-1998050029-A1 | INHIBITORS OF PROTEIN ISOPRENYL TRANSFERASES | UNIVERSITY OF PITTSBURGH (US) | 1998-11-12 | — | — | WO | disclosed |