Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH1A | P07327 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | ADH1C | P00326 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL628951 | 0.88 | L3MBTL1 (0.42) | ADH1AHSD11B1L3MBTL1ADH1C | |
| SCHEMBL9632418 | 0.82 | THRA (0.43) | ADH1AADH1C | |
| SCHEMBL9632611 | 0.82 | THRA (0.43) | ADH1AADH1C | |
| SCHEMBL5510945 | 0.78 | L3MBTL1 (0.42) | ADH1AHSD11B1L3MBTL1ADH1C | |
| SCHEMBL4281691 | 0.78 | ADH1A (0.48) | ADH1AL3MBTL1ADH1C | |
| SCHEMBL9462350 | 0.76 | ADH1A (0.47) | ADH1AL3MBTL1ADH1C | |
| SCHEMBL6627701 | 0.74 | ALDH1A1 (0.41) | L3MBTL1 | |
| SCHEMBL13911314 | 0.74 | ADH1A (0.44) | ADH1AL3MBTL1ADH1C | |
| Acetic Acid SCHEMBL7705514 | 0.74 | EPHX1 (0.47) | — | |
| SCHEMBL9071877 | 0.73 | L3MBTL1 (0.41) | ADH1AHSD11B1L3MBTL1ADH1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0986384-A4 | INHIBITORS OF PROTEIN ISOPRENYL TRANSFERASES | UNIV PITTSBURGH (US) | 2004-09-15 | — | — | EP | disclosed |
| EP-0986384-A1 | INHIBITORS OF PROTEIN ISOPRENYL TRANSFERASES | UNIVERSITY OF PITTSBURGH (US) | 2000-03-22 | — | — | EP | disclosed |
| WO-1998050029-A1 | INHIBITORS OF PROTEIN ISOPRENYL TRANSFERASES | UNIVERSITY OF PITTSBURGH (US) | 1998-11-12 | — | — | WO | disclosed |