SCHEMBL6627745

SCHEMBL6627745

CC1C=C(c2ccccc2)c2ccccc21

nearest known ligand 0.37

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.37
MAPK1 P28482 1/20 0.37
GPR3 P46089 2/20 0.34
PTPN1 P18031 2/20 0.34
PTPRC P08575 1/20 0.34
PTPRF P10586 1/20 0.34
CDC25B P30305 1/20 0.34
BACE1 P56817 1/20 0.34
BRD4 O60885 1/20 0.33
HSD17B10 Q99714 2/20 0.32
HPGD P15428 1/20 0.32
BCL2L1 Q07817 1/20 0.32
CYP2A6 P11509 1/20 0.32
CHRNB2 P17787 1/20 0.32
CHRNA4 P43681 1/20 0.32
MEN1 O00255 1/20 0.32
POLB P06746 1/20 0.32
KMT2A Q03164 1/20 0.32
ATM Q13315 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2962267 0.80 MAPK1 (0.38) ALDH1A1MAPK1PTPRCHPGDCYP2A6
SCHEMBL2973762 0.80 MAPK1 (0.40) ALDH1A1MAPK1PTPRCBRD4HPGD
SCHEMBL28849090 0.77 ALDH1A1 (0.38) ALDH1A1MAPK1GPR3PTPN1PTPRC
SCHEMBL28303653 0.75 BACE1 (0.38) ALDH1A1MAPK1GPR3PTPN1PTPRC
SCHEMBL28806317 0.75 ALDH1A1 (0.37) ALDH1A1MAPK1PTPN1PTPRCPTPRF
SCHEMBL3383290 0.75 ALDH1A1 (0.33) ALDH1A1MAPK1GPR3PTPN1PTPRC
SCHEMBL28351851 0.75 ALDH1A1 (0.33) ALDH1A1MAPK1GPR3PTPN1PTPRC
SCHEMBL7542406 0.75 ALDH1A1 (0.33) ALDH1A1MAPK1GPR3PTPN1PTPRC
SCHEMBL28782651 0.74 GPR3 (0.37) ALDH1A1MAPK1GPR3PTPRCPOLB
SCHEMBL29281412 0.73 ALDH1A1 (0.35) ALDH1A1MAPK1PTPN1PTPRCPTPRF

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116514628-A Synthesis method of 1-methyl-3-phenylindene 南京神奇科技开发有限公司 2023-08-01 CN claimed
CN-116514628-A Synthesis method of 1-methyl-3-phenylindene 南京神奇科技开发有限公司 2023-08-01 CN disclosed
CN-116514628-A Synthesis method of 1-methyl-3-phenylindene 南京神奇科技开发有限公司 2023-08-01 CN disclosed
CN-116514628-A Synthesis method of 1-methyl-3-phenylindene 南京神奇科技开发有限公司 2023-08-01 CN disclosed
EP-1033130-B1 INHIBITOR OF UROKINASE PRODUCTION AND OF ANGIOGENESIS AND ITS THERAPEUTIC USE TAIHO PHARMACEUTICAL CO LTD (JP) 2004-04-21 EP disclosed
EP-0798306-B1 Substituted indenyl unbridged metallocenes PHILLIPS PETROLEUM CO (US) 2002-05-22 EP disclosed
US-6365610-B1 1,4-EPOXY-2,3-BENZODIOXEPINS OR 1,4-EPOXY-3,2-BENZOXAZEPINES TAIHO PHARMACEUTICAL COMPANY LTD. (JP) 2002-04-02 US disclosed
CN-1065868-C substituted indenyl unbridged metallocenes PHILLIPS PETROLEUM CO (US) 2001-05-16 CN disclosed
EP-1033130-A1 UROKINASE PRODUCTION INHIBITORS, ANGIOGENESIS INHIBITORS AND METHODS OF PREVENTION OR TREATMENT WITH BOTH TAIHO PHARMACEUTICAL COMPANY LIMITED (JP) 2000-09-06 EP disclosed
US-6037427-A UNBRIDGED METALLOCENE CATALYSTS USED IN COMBINATION WITH SUITABLE COCATALYST FOR THE POLYMERIZATION OF OLEFINIC MONOMERS SCHMID CLAUDIA (DE) 2000-03-14 US disclosed
US-5780659-A ADDITION POLYMERIZATION CATALYSTS PHILLIPS PETROLEUM COMPANY (US) 1998-07-14 US disclosed
CN-1164535-A Substituted indenyl unbridged metallocenes PHILLIPS PETROLEUM CO (US) 1997-11-12 CN disclosed
EP-0798306-A1 Substituted indenyl unbridged metallocenes PHILLIPS PETROLEUM COMPANY (US) 1997-10-01 EP disclosed
US-4151182-A CATALYTIC OXIDATION FROM INDANS OR DIPHENYLMETHANE DERIVATIVES BADISCHE ANILIN- & SODA-FABRIK AKTIENGESELLSCHAFT (DE) 1979-04-24 US disclosed