Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 2/20 | 0.32 |
| ▸ | HTR7 | P34969 | 2/20 | 0.32 |
| ▸ | HTR2B | P41595 | 2/20 | 0.32 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.32 |
| ▸ | PTPRC | P08575 | 1/20 | 0.32 |
| ▸ | PTPRF | P10586 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | CDC25B | P30305 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20528820 | 0.79 | NPC1 (0.30) | ALDH1A1RAB9ANPC1TSHRSMN1; SMN2 | |
| SCHEMBL31185423 | 0.76 | — | — | |
| SCHEMBL23141288 | 0.76 | — | — | |
| SCHEMBL29897864 | 0.76 | — | — | |
| SCHEMBL7542646 | 0.75 | GPR3 (0.34) | RAB9ANPC1SMN1; SMN2GPR3KMT2A | |
| SCHEMBL21840762 | 0.74 | KDR (0.30) | — | |
| SCHEMBL29960999 | 0.74 | KDR (0.30) | — | |
| SCHEMBL29979921 | 0.73 | GPR3 (0.33) | GPR3 | |
| SCHEMBL7542082 | 0.73 | GPR3 (0.33) | GPR3 | |
| SCHEMBL28849090 | 0.72 | ALDH1A1 (0.38) | ALDH1A1MAPK1HPGDPTPRCPTPRF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0798306-B1 | Substituted indenyl unbridged metallocenes | PHILLIPS PETROLEUM CO (US) | 2002-05-22 | — | — | EP | disclosed |
| US-6037427-A | UNBRIDGED METALLOCENE CATALYSTS USED IN COMBINATION WITH SUITABLE COCATALYST FOR THE POLYMERIZATION OF OLEFINIC MONOMERS | SCHMID CLAUDIA (DE) | 2000-03-14 | — | — | US | disclosed |
| US-5780659-A | ADDITION POLYMERIZATION CATALYSTS | PHILLIPS PETROLEUM COMPANY (US) | 1998-07-14 | — | — | US | disclosed |
| EP-0798306-A1 | Substituted indenyl unbridged metallocenes | PHILLIPS PETROLEUM COMPANY (US) | 1997-10-01 | — | — | EP | disclosed |