SCHEMBL6628233

SCHEMBL6628233

CCC(C(=O)O)N1CCN(CC(=O)O)CCN(C(CO)C(=O)O)CCN(C(C)C(=O)O)CC1

nearest known ligand 0.42

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
SLC6A9 P48067 1/20 0.36
TACR1 P25103 2/20 0.33
KDM4E B2RXH2 1/20 0.33
HSD17B10 Q99714 1/20 0.33
SIGMAR1 Q99720 1/20 0.32
ALB P02768 1/20 0.31
S1PR1 P21453 1/20 0.30
MME P08473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6626285 0.94 SLC6A9 (0.39) SLC6A9TACR1KDM4EHSD17B10SIGMAR1
SCHEMBL6625088 0.94 SLC6A9 (0.39) SLC6A9TACR1KDM4EHSD17B10SIGMAR1
SCHEMBL12156561 0.87 SLC6A9 (0.44) SLC6A9TACR1KDM4EHSD17B10SIGMAR1
SCHEMBL408919 0.87 SLC6A9 (0.44) SLC6A9TACR1KDM4EHSD17B10SIGMAR1
SCHEMBL12156548 0.87 SLC6A9 (0.44) SLC6A9TACR1KDM4EHSD17B10SIGMAR1
SCHEMBL7593926 0.87 SLC6A9 (0.44) SLC6A9TACR1KDM4EHSD17B10SIGMAR1
SCHEMBL6623787 0.85 CHRM5 (0.40) SLC6A9TACR1KDM4EHSD17B10SIGMAR1
Hydrochloric Acid SCHEMBL29697028 0.85 SLC6A9 (0.43) SLC6A9TACR1KDM4EHSD17B10SIGMAR1
SCHEMBL5370149 0.85 SLC6A9 (0.45) SLC6A9TACR1HSD17B10ALBS1PR1
SCHEMBL5551081 0.85 SLC6A9 (0.45) SLC6A9TACR1HSD17B10ALBS1PR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0998476-B1 1,4,7,10-TETRAAZABICYCLO 8.2.2]TETRADECAN-2-ONE, A PROCESS FOR THE PREPARATION THEREOF AND THE USE THEREOF FOR THE PREPARATION OF TETRAAZAMACROCYCLES BRACCO SPA (IT) 2004-05-06 EP disclosed
US-6162912-A Process of preparing tetraacetic acid derivatives DIBRA S.P.A. (IT) 2000-12-19 US disclosed
US-6048980-A AMINATION WITH DEHYDROHALOGENATION FOLLOWED BY HYDROLYSIS OF ESTER GROUP DIBRA S.P.A (IT) 2000-04-11 US disclosed
US-6028194-A SYNTHESIS OF GADOTERIDOL AND GADOBUTROL CONTRAST AGENTS FOR THE RESONANCE TECHNIQUE (MAGNETIC RESONANCE IMAGING) DIBRA S.P.A. (IT) 2000-02-22 US disclosed
US-6020485-A Process for producing tetraazabicyclo monoacetic acid DIBRA S.P.A. (IT) 2000-02-01 US disclosed
US-5977353-A 1,4,7,10-tetraazabicyclo[8.2.2]tetradecan-2-one, a process for the preparation thereof and the use thereof for the preparation of tetraazamacrocycles DIBRA S.P.A. (IT) 1999-11-02 US disclosed