Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TACR1 | P25103 | 3/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MME | P08473 | 1/20 | 0.33 |
| ▸ | ALB | P02768 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6628233 | 0.94 | SLC6A9 (0.36) | SLC6A9HSD17B10TACR1SIGMAR1KDM4E | |
| SCHEMBL5551081 | 0.90 | SLC6A9 (0.45) | SLC6A9HSD17B10TACR1ALBMEN1 | |
| SCHEMBL6628577 | 0.90 | SLC6A9 (0.45) | SLC6A9HSD17B10TACR1ALBMEN1 | |
| SCHEMBL6625142 | 0.90 | SLC6A9 (0.45) | SLC6A9HSD17B10TACR1ALBMEN1 | |
| SCHEMBL5370149 | 0.90 | SLC6A9 (0.45) | SLC6A9HSD17B10TACR1ALBMEN1 | |
| SCHEMBL7590528 | 0.88 | SLC6A9 (0.46) | SLC6A9HSD17B10TACR1SIGMAR1KDM4E | |
| SCHEMBL13223371 | 0.88 | SLC6A9 (0.46) | SLC6A9HSD17B10TACR1SIGMAR1KDM4E | |
| SCHEMBL5033230 | 0.88 | SLC6A9 (0.46) | SLC6A9HSD17B10TACR1SIGMAR1KDM4E | |
| SCHEMBL16582365 | 0.88 | SLC6A9 (0.46) | SLC6A9HSD17B10TACR1SIGMAR1KDM4E | |
| SCHEMBL16382945 | 0.88 | SLC6A9 (0.46) | SLC6A9HSD17B10TACR1SIGMAR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0998476-B1 | 1,4,7,10-TETRAAZABICYCLO 8.2.2]TETRADECAN-2-ONE, A PROCESS FOR THE PREPARATION THEREOF AND THE USE THEREOF FOR THE PREPARATION OF TETRAAZAMACROCYCLES | BRACCO SPA (IT) | 2004-05-06 | — | — | EP | disclosed |
| US-6162912-A | Process of preparing tetraacetic acid derivatives | DIBRA S.P.A. (IT) | 2000-12-19 | — | — | US | disclosed |
| US-6028194-A | SYNTHESIS OF GADOTERIDOL AND GADOBUTROL CONTRAST AGENTS FOR THE RESONANCE TECHNIQUE (MAGNETIC RESONANCE IMAGING) | DIBRA S.P.A. (IT) | 2000-02-22 | — | — | US | disclosed |
| US-6020485-A | Process for producing tetraazabicyclo monoacetic acid | DIBRA S.P.A. (IT) | 2000-02-01 | — | — | US | disclosed |
| US-5977353-A | 1,4,7,10-tetraazabicyclo[8.2.2]tetradecan-2-one, a process for the preparation thereof and the use thereof for the preparation of tetraazamacrocycles | DIBRA S.P.A. (IT) | 1999-11-02 | — | — | US | disclosed |