Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAM17 | P78536 | 13/20 | 0.41 |
| ▸ | MMP3 | P08254 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 2/20 | 0.40 |
| ▸ | MMP2 | P08253 | 6/20 | 0.38 |
| ▸ | MMP9 | P14780 | 5/20 | 0.38 |
| ▸ | LIPE | Q05469 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL6626825 | 0.82 | ADAM17 (0.62) | ADAM17MMP3MMP1MMP2MMP9 | |
| Trifluoroacetic Acid SCHEMBL6629402 | 0.81 | ADAM17 (0.51) | ADAM17MMP3MMP1MMP2MMP9 | |
| Trifluoroacetic Acid SCHEMBL6626541 | 0.81 | ADAM17 (0.53) | ADAM17MMP3MMP1MMP2MMP9 | |
| Trifluoroacetic Acid SCHEMBL6626798 | 0.81 | ADAM17 (0.53) | ADAM17MMP3MMP1MMP2MMP9 | |
| Trifluoroacetic Acid SCHEMBL6631779 | 0.81 | ADAM17 (0.53) | ADAM17MMP3MMP1MMP2MMP9 | |
| Trifluoroacetic Acid SCHEMBL6629485 | 0.81 | ADAM17 (0.52) | ADAM17MMP3MMP1MMP2MMP9 | |
| Trifluoroacetic Acid SCHEMBL6627253 | 0.81 | ADAM17 (0.52) | ADAM17MMP3MMP1MMP2MMP9 | |
| Trifluoroacetic Acid SCHEMBL6626945 | 0.80 | ADAM17 (0.52) | ADAM17MMP3MMP1MMP2MMP9 | |
| Trifluoroacetic Acid SCHEMBL6628321 | 0.80 | ADAM17 (0.52) | ADAM17MMP3MMP1MMP2MMP9 | |
| SCHEMBL6628834 | 0.73 | ADAM17 (0.62) | ADAM17MMP1MMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1027332-B1 | NOVEL LACTAM METALLOPROTEASE INHIBITORS | BRISTOL MYERS SQUIBB PHARMA CO (US) | 2004-05-26 | — | — | EP | disclosed |